CN132_HUMAN
ID CN132_HUMAN Reviewed; 83 AA.
AC Q9NPU4; B2R7K5;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 04-MAR-2015, sequence version 2.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein C14orf132 {ECO:0000305};
GN Name=C14orf132 {ECO:0000312|HGNC:HGNC:20346};
GN Synonyms=C14orf88 {ECO:0000312|HGNC:HGNC:20346};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
RN [2]
RP PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Cerebellum;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Amygdala;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D.,
RA Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A.,
RA Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [4]
RP PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAG35852.1; Type=Erroneous translation; Evidence={ECO:0000305};
CC Sequence=CAB99085.1; Type=Erroneous translation; Evidence={ECO:0000305};
CC Sequence=EAW81627.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL137190; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK313017; BAG35852.1; ALT_SEQ; mRNA.
DR EMBL; AL390130; CAB99085.1; ALT_SEQ; mRNA.
DR EMBL; CH471061; EAW81627.1; ALT_SEQ; Genomic_DNA.
DR CCDS; CCDS81848.1; -.
DR PIR; T51868; T51868.
DR RefSeq; NP_001239436.1; NM_001252507.2.
DR RefSeq; NP_001269393.1; NM_001282464.1.
DR AlphaFoldDB; Q9NPU4; -.
DR BioMuta; C14orf132; -.
DR PRIDE; Q9NPU4; -.
DR Antibodypedia; 48894; 2 antibodies from 2 providers.
DR DNASU; 56967; -.
DR Ensembl; ENST00000555004.3; ENSP00000490729.1; ENSG00000227051.7.
DR Ensembl; ENST00000556728.1; ENSP00000490894.1; ENSG00000227051.7.
DR GeneID; 56967; -.
DR KEGG; hsa:56967; -.
DR MANE-Select; ENST00000555004.3; ENSP00000490729.1; NM_001252507.3; NP_001239436.1.
DR CTD; 56967; -.
DR GeneCards; C14orf132; -.
DR HGNC; HGNC:20346; C14orf132.
DR HPA; ENSG00000227051; Tissue enhanced (brain).
DR neXtProt; NX_Q9NPU4; -.
DR OpenTargets; ENSG00000227051; -.
DR VEuPathDB; HostDB:ENSG00000227051; -.
DR GeneTree; ENSGT00700000106116; -.
DR InParanoid; Q9NPU4; -.
DR OMA; FMDSSNE; -.
DR PathwayCommons; Q9NPU4; -.
DR BioGRID-ORCS; 56967; 9 hits in 301 CRISPR screens.
DR ChiTaRS; C14orf132; human.
DR GenomeRNAi; 56967; -.
DR Pharos; Q9NPU4; Tdark.
DR PRO; PR:Q9NPU4; -.
DR Proteomes; UP000005640; Chromosome 14.
DR RNAct; Q9NPU4; protein.
DR Bgee; ENSG00000227051; Expressed in middle temporal gyrus and 182 other tissues.
DR ExpressionAtlas; Q9NPU4; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..83
FT /note="Uncharacterized protein C14orf132"
FT /id="PRO_0000089934"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 83 AA; 8830 MW; 94484D83115F30E1 CRC64;
MDLSFMAAQL PMMGGAFMDS PNEDFSTEYS LFNSSANVHA AANGQGQPED PPRSSNDAVL
LWIAIIATLG NIVVVGVVYA FTF
