ID   CNFN_BOVIN              Reviewed;         111 AA.
AC   Q0VBW2;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Cornifelin;
GN   Name=CNFN;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the insoluble cornified cell envelope (CE) of
CC       stratified squamous epithelia.
CC   -!- SUBUNIT: Directly or indirectly cross-linked to CE proteins loricin and
CC       involucrin (IVL). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=Constituent of the scaffolding of
CC       the cornified envelope. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cornifelin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC120481; AAI20482.1; -; mRNA.
DR   RefSeq; NP_001069010.1; NM_001075542.1.
DR   RefSeq; XP_005219294.1; XM_005219237.2.
DR   AlphaFoldDB; Q0VBW2; -.
DR   STRING; 9913.ENSBTAP00000041423; -.
DR   PaxDb; Q0VBW2; -.
DR   PRIDE; Q0VBW2; -.
DR   GeneID; 511870; -.
DR   KEGG; bta:511870; -.
DR   CTD; 84518; -.
DR   eggNOG; ENOG502S8N3; Eukaryota.
DR   HOGENOM; CLU_083147_5_2_1; -.
DR   InParanoid; Q0VBW2; -.
DR   OrthoDB; 1354725at2759; -.
DR   TreeFam; TF330308; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0001533; C:cornified envelope; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   InterPro; IPR006461; PLAC_motif_containing.
DR   PANTHER; PTHR15907; PTHR15907; 1.
DR   Pfam; PF04749; PLAC8; 1.
DR   TIGRFAMs; TIGR01571; A_thal_Cys_rich; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Keratinization; Reference proteome.
FT   CHAIN           1..111
FT                   /note="Cornifelin"
FT                   /id="PRO_0000261194"
SQ   SEQUENCE   111 AA;  12313 MW;  E496F47C1B2CE7B0 CRC64;
     MSYPVTSQPQ SASTCYQTQL SDWHTGLTDC CNDMPVCLCG TFAPLCLACR ISDDFGECCC
     TPYLPGGLHS LRTGMRERYR IQGSIGKDWA ALTFCLPCAL CQMARELKIR E