ID   CNIH2_ARATH             Reviewed;         129 AA.
AC   Q3EDD7; Q9LNB1;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Probable protein cornichon homolog 2;
GN   OrderedLocusNames=At1g12340; ORFNames=F5O11.7;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cornichon family. {ECO:0000305}.
CC   -!- CAUTION: Lacks one of the three transmembrane regions, which are
CC       conserved features of the family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF79631.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g12340 and At1g12350.; Evidence={ECO:0000305};
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DR   EMBL; AC025416; AAF79631.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE28868.1; -; Genomic_DNA.
DR   RefSeq; NP_563903.2; NM_101106.2.
DR   AlphaFoldDB; Q3EDD7; -.
DR   SMR; Q3EDD7; -.
DR   STRING; 3702.AT1G12340.1; -.
DR   PaxDb; Q3EDD7; -.
DR   PRIDE; Q3EDD7; -.
DR   EnsemblPlants; AT1G12340.1; AT1G12340.1; AT1G12340.
DR   GeneID; 837788; -.
DR   Gramene; AT1G12340.1; AT1G12340.1; AT1G12340.
DR   KEGG; ath:AT1G12340; -.
DR   Araport; AT1G12340; -.
DR   TAIR; locus:2034655; AT1G12340.
DR   eggNOG; KOG2729; Eukaryota.
DR   HOGENOM; CLU_112942_3_1_1; -.
DR   OMA; HFMSVIV; -.
DR   OrthoDB; 1602458at2759; -.
DR   PhylomeDB; Q3EDD7; -.
DR   PRO; PR:Q3EDD7; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q3EDD7; baseline and differential.
DR   Genevisible; Q3EDD7; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR003377; Cornichon.
DR   Pfam; PF03311; Cornichon; 1.
DR   SMART; SM01398; Cornichon; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..129
FT                   /note="Probable protein cornichon homolog 2"
FT                   /id="PRO_0000398827"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   129 AA;  15379 MW;  2977DF343860B1C1 CRC64;
     MRGVTETDKL ANGIFHLVCL ADLEFDYINP YDSASRINSV VLPEFIVQGV LCVFYLLTGH
     WFMTLLCLPY LYYNFHLYSK RQHLVDVTEI FNLLNWEKKK RLFKLAYIVL NLFLTIFWMI
     YSALDDYED