ID   CNIH2_ORYSJ             Reviewed;         149 AA.
AC   Q2QQ55; Q0IN59;
DT   03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Protein cornichon homolog 2 {ECO:0000305};
GN   Name=CNIH2 {ECO:0000305};
GN   OrderedLocusNames=Os12g0506400 {ECO:0000312|EMBL:BAT17291.1},
GN   LOC_Os12g32180 {ECO:0000312|EMBL:ABA98682.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- FUNCTION: Acts as cargo receptor necessary for the transportation of
CC       secretory proteins from the endoplasmic reticulum (ER) in COPII-coated
CC       vesicles targeted to the Golgi apparatus.
CC       {ECO:0000250|UniProtKB:Q0DET3}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:Q0DET3}; Multi-pass membrane protein
CC       {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q0DET3};
CC       Multi-pass membrane protein {ECO:0000255}. Note=Located primarily in
CC       the endoplasmic reticulum (ER); may cycle between the ER and the Golgi
CC       apparatus. {ECO:0000250|UniProtKB:Q0DET3}.
CC   -!- SIMILARITY: Belongs to the cornichon family. {ECO:0000305}.
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DR   EMBL; DP000011; ABA98682.1; -; Genomic_DNA.
DR   EMBL; AP008218; BAF29856.1; -; Genomic_DNA.
DR   EMBL; AP014968; BAT17291.1; -; Genomic_DNA.
DR   EMBL; AK060944; BAG87633.1; -; mRNA.
DR   RefSeq; XP_015620299.1; XM_015764813.1.
DR   SMR; Q2QQ55; -.
DR   STRING; 39947.Q2QQ55; -.
DR   PRIDE; Q2QQ55; -.
DR   EnsemblPlants; Os12t0506400-01; Os12t0506400-01; Os12g0506400.
DR   GeneID; 4352293; -.
DR   Gramene; Os12t0506400-01; Os12t0506400-01; Os12g0506400.
DR   KEGG; osa:4352293; -.
DR   eggNOG; KOG2729; Eukaryota.
DR   HOGENOM; CLU_112942_3_0_1; -.
DR   OMA; YDPAEIH; -.
DR   OrthoDB; 1602458at2759; -.
DR   Proteomes; UP000000763; Chromosome 12.
DR   Proteomes; UP000059680; Chromosome 12.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR003377; Cornichon.
DR   Pfam; PF03311; Cornichon; 1.
DR   SMART; SM01398; Cornichon; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..149
FT                   /note="Protein cornichon homolog 2"
FT                   /id="PRO_0000455964"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   149 AA;  17491 MW;  BD1E140ABE114122 CRC64;
     MSIELILWLF SFASIMVLIG LTAYQLICLS DLEFDYINPY DSSSRINSVV LIEYALQGAL
     CASFLLTLHW FPFLVMAPVA YYHGKLYMDR KHLVDVTEIF RQLNWEKKYR MIKLAFYFSL
     FIITIYRLVM TAVTLFIDED ANLVDTRTI