ID   CNP2_CAEEL              Reviewed;         732 AA.
AC   Q9U2D6;
DT   06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 3.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Calcineurin-interacting protein 2 {ECO:0000303|PubMed:18593529};
DE   AltName: Full=Calcineurin binding protein 2 {ECO:0000312|WormBase:Y46G5A.10};
GN   Name=cnp-2 {ECO:0000312|WormBase:Y46G5A.10};
GN   ORFNames=Y46G5A.10 {ECO:0000312|WormBase:Y46G5A.10};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000312|Proteomes:UP000001940};
RN   [1] {ECO:0000312|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000312|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2] {ECO:0000305}
RP   INTERACTION WITH TAX-6, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP   DISRUPTION PHENOTYPE.
RX   PubMed=18593529; DOI=10.5483/bmbrep.2008.41.6.455;
RA   Xianglan C., Ko K.M., Singaravelu G., Ahnn J.;
RT   "Novel calcineurin interacting protein-2: the functional characterization
RT   of CNP-2 in Caenorhabditis elegans.";
RL   BMB Rep. 41:455-460(2008).
CC   -!- SUBUNIT: Interacts with tax-6. {ECO:0000269|PubMed:18593529}.
CC   -!- TISSUE SPECIFICITY: Expressed in intestine.
CC       {ECO:0000269|PubMed:18593529}.
CC   -!- DEVELOPMENTAL STAGE: Expressed from the gastrula stage throughout
CC       adulthood. {ECO:0000269|PubMed:18593529}.
CC   -!- DISRUPTION PHENOTYPE: RNAi-mediated knockdown results in no obvious
CC       phenotype. {ECO:0000269|PubMed:18593529}.
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DR   EMBL; BX284602; CAB60376.3; -; Genomic_DNA.
DR   RefSeq; NP_496715.3; NM_064314.5.
DR   AlphaFoldDB; Q9U2D6; -.
DR   DIP; DIP-26531N; -.
DR   IntAct; Q9U2D6; 5.
DR   STRING; 6239.Y46G5A.10; -.
DR   EPD; Q9U2D6; -.
DR   PaxDb; Q9U2D6; -.
DR   PeptideAtlas; Q9U2D6; -.
DR   PRIDE; Q9U2D6; -.
DR   EnsemblMetazoa; Y46G5A.10.1; Y46G5A.10.1; WBGene00012901.
DR   GeneID; 174907; -.
DR   KEGG; cel:CELE_Y46G5A.10; -.
DR   UCSC; Y46G5A.10; c. elegans.
DR   CTD; 174907; -.
DR   WormBase; Y46G5A.10; CE37941; WBGene00012901; cnp-2.
DR   eggNOG; ENOG502QWCT; Eukaryota.
DR   GeneTree; ENSGT00940000167855; -.
DR   HOGENOM; CLU_378669_0_0_1; -.
DR   InParanoid; Q9U2D6; -.
DR   OMA; RENTWTP; -.
DR   OrthoDB; 1053597at2759; -.
DR   Reactome; R-CEL-913709; O-linked glycosylation of mucins.
DR   PRO; PR:Q9U2D6; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00012901; Expressed in material anatomical entity and 5 other tissues.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..732
FT                   /note="Calcineurin-interacting protein 2"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000436778"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          115..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          310..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..708
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..163
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..223
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..508
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..537
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        600..628
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        676..701
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   732 AA;  84401 MW;  6999DDB9B5815C58 CRC64;
     MNRGYDSYNR SRSTSSRPLD REPYHAVSEL YTKEITHTPI GPASDLPPEI LDILKENPRA
     TPQYTPPLIR HRENTWTPEN YPIVRVPSAQ FTDVMTELYD YHEVEKYTHR SVTPDYEPLR
     KEPELKEQKL PTYQVIPPTP EKNTPRHQHH SGITLSPSDS SRTLGALPKK PPMYEEYLQM
     QKKDENRNIP RQVSSADSQR TIRNNNELSH LRHIDSSSSS EASEPAKDLD DRERYVYTHD
     VYVDSTTGRP FTPGREDVRE KKNCDKLKIN VYFKPPHPPV EITYKLDEIE IEKNENIVVT
     KLRPSRSDTI LSRSVSTSPS SVTDNIPKTS TSRIPSSENP KTMEHTTTSR RFPTQTSILR
     KEHEIVQVPL HRSQSLRQSR ISEHSKRSLG KTTSTVSTER PIPIHVVEET SSIDMDVVFP
     KMPHHQTVTN VRVPSSRGSA ISRAHSEHRR SIDRSEPRHH HRHHVHSETP ELPYTRGISK
     TPSVREYNVK REGQRSPSRS HRSERSPSEV RIPVTTTHTR PIAKRQSPEE LDYGRFADKS
     QQNRFPGDHQ AREEDLPYTR GISKTPSNQD SRSERTPCSD IHIPYNNPEK ERAYQQSERS
     SYRSHKSVTP SEKSLPRNSE TPELHYTRGI SKTPSDRVEK SRYLSRGVST PHTPSEVHIP
     YNNPEKERAY QQSHRPSSPK RRPSGRTNSP NKSSSSSKAR PSAAPLEEIV HIKERYERDE
     TIRRFFPTTT AV