CNP3_CAEEL
ID CNP3_CAEEL Reviewed; 533 AA.
AC O02039;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Calcineurin-interacting protein 3 {ECO:0000303|PubMed:18460897};
DE AltName: Full=Calcineurin binding protein 3 {ECO:0000312|WormBase:T23C6.3};
GN Name=cnp-3 {ECO:0000312|WormBase:T23C6.3};
GN ORFNames=T23C6.3 {ECO:0000312|WormBase:T23C6.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000312|Proteomes:UP000001940};
RN [1] {ECO:0000312|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000312|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION, AND DEVELOPMENTAL STAGE.
RX PubMed=18460897;
RA Kim Y.H., Song H.O., Ko K.M., Singaravelu G., Jee C., Kang J., Ahnn J.;
RT "A novel calcineurin-interacting protein, CNP-3, modulates calcineurin
RT deficient phenotypes in Caenorhabditis elegans.";
RL Mol. Cells 25:566-571(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18460897}.
CC -!- DEVELOPMENTAL STAGE: Expression begins at the gastrulation stage.
CC Expressed predominantly in the intestine from the comma stage onwards.
CC In early larval stages, expressed in hypodermis and intestine. At L3
CC larval stage expressed transiently in spermatheca and dorsal uterus.
CC {ECO:0000269|PubMed:18460897}.
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DR EMBL; BX284606; CCD61704.1; -; Genomic_DNA.
DR PIR; T15116; T15116.
DR RefSeq; NP_510776.1; NM_078375.5.
DR AlphaFoldDB; O02039; -.
DR SMR; O02039; -.
DR IntAct; O02039; 1.
DR STRING; 6239.T23C6.3; -.
DR EPD; O02039; -.
DR PaxDb; O02039; -.
DR EnsemblMetazoa; T23C6.3.1; T23C6.3.1; WBGene00020725.
DR GeneID; 181752; -.
DR KEGG; cel:CELE_T23C6.3; -.
DR UCSC; T23C6.3.1; c. elegans.
DR CTD; 181752; -.
DR WormBase; T23C6.3; CE07528; WBGene00020725; cnp-3.
DR eggNOG; ENOG502TGY3; Eukaryota.
DR GeneTree; ENSGT00970000196737; -.
DR HOGENOM; CLU_464008_0_0_1; -.
DR InParanoid; O02039; -.
DR OMA; FLNHAFQ; -.
DR OrthoDB; 1701721at2759; -.
DR PRO; PR:O02039; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00020725; Expressed in embryo and 4 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..533
FT /note="Calcineurin-interacting protein 3"
FT /evidence="ECO:0000305"
FT /id="PRO_0000436925"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 61479 MW; 6CEC25B2A05E3335 CRC64;
MRSLKRENSG SALSVRSSDS EGDSYHNMDI KKLTNKVKEI DISAFDRTRL FNPRKQRSCH
KRAEPVSEEH RKKESSKNSR EYTKRNRDEI VTCQKLFSEI TAIMRRFKQL TEEMSVETVE
VKIKSMIKDC QEMLTKYTNL DSNDRFNIGI PEAEDFLAIF REKAHATMLF EHRPESPNMY
TENLFKLREQ YHKLTDHKDN LNSSKDKTNY ASSKSRLNQR IVREQLKSDC WVCWKSINTM
MVQGEQLQEY NNELKKDIWN NILAVYHQIF TMFCKYPEYA DKEKMERIVE YFAPVSRTPG
HLSVVWNPMP NVVKSPRSEE IPEIKVEYEE VPSSSTFLSN NETTIASDMD MSIDRPQSMD
MSQTLSPEQT LSPREKLQVQ DRKISTTQET PPALPSPSGT LTLPTVPAST LKRKEFGDLL
ACPTGKRVTI DEPNRAERTE TIMPSRQMMY PMVNYQALPM PPQSIPSMIP PFIPTIPSTS
TMPPMMPYPN VLLTAAPGDV APIDSLTPSF LRALEQQKLM AAFLNHAFQK CQK