ID   CNPD1_MOUSE             Reviewed;         407 AA.
AC   Q8K158; Q3TE87;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Protein CNPPD1;
GN   Name=Cnppd1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=NOD; TISSUE=Thymus;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N; TISSUE=Liver;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CNPPD1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC028815; AAH28815.1; -; mRNA.
DR   EMBL; AK029090; BAC26289.1; -; mRNA.
DR   EMBL; AK169779; BAE41361.1; -; mRNA.
DR   CCDS; CCDS15063.1; -.
DR   RefSeq; NP_081253.1; NM_026977.2.
DR   RefSeq; XP_006496603.1; XM_006496540.2.
DR   RefSeq; XP_006496604.1; XM_006496541.2.
DR   RefSeq; XP_006496605.1; XM_006496542.2.
DR   AlphaFoldDB; Q8K158; -.
DR   SMR; Q8K158; -.
DR   STRING; 10090.ENSMUSP00000132688; -.
DR   PhosphoSitePlus; Q8K158; -.
DR   PaxDb; Q8K158; -.
DR   PRIDE; Q8K158; -.
DR   Antibodypedia; 47668; 69 antibodies from 17 providers.
DR   DNASU; 69171; -.
DR   Ensembl; ENSMUST00000041213; ENSMUSP00000044799; ENSMUSG00000033159.
DR   Ensembl; ENSMUST00000168720; ENSMUSP00000132688; ENSMUSG00000033159.
DR   Ensembl; ENSMUST00000190679; ENSMUSP00000140289; ENSMUSG00000033159.
DR   GeneID; 69171; -.
DR   KEGG; mmu:69171; -.
DR   UCSC; uc007bnp.1; mouse.
DR   CTD; 27013; -.
DR   MGI; MGI:1916421; Cnppd1.
DR   VEuPathDB; HostDB:ENSMUSG00000033159; -.
DR   eggNOG; KOG1674; Eukaryota.
DR   GeneTree; ENSGT00390000000862; -.
DR   HOGENOM; CLU_051510_0_0_1; -.
DR   InParanoid; Q8K158; -.
DR   OMA; GPPSPWY; -.
DR   OrthoDB; 1276824at2759; -.
DR   PhylomeDB; Q8K158; -.
DR   TreeFam; TF105853; -.
DR   BioGRID-ORCS; 69171; 0 hits in 75 CRISPR screens.
DR   ChiTaRS; Cnppd1; mouse.
DR   PRO; PR:Q8K158; -.
DR   Proteomes; UP000000589; Chromosome 1.
DR   RNAct; Q8K158; protein.
DR   Bgee; ENSMUSG00000033159; Expressed in granulocyte and 248 other tissues.
DR   ExpressionAtlas; Q8K158; baseline and differential.
DR   Genevisible; Q8K158; MM.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   InterPro; IPR013922; Cyclin_PHO80-like.
DR   PANTHER; PTHR15615; PTHR15615; 1.
DR   Pfam; PF08613; Cyclin; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..407
FT                   /note="Protein CNPPD1"
FT                   /id="PRO_0000089353"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   407 AA;  44915 MW;  8F0BA35201251FB7 CRC64;
     MDLTGLLLDE EGAFSLTGFQ DFMVLPGHQK LSARIRRRLY YGWDLETDCS LEELSSPVAD
     ITVELLQKAA PSPIRRLQKK YVAHVSREAC ISPCAMMLAL VYIERLRHRN PDYLQHVSSS
     DLFLISMMVA SKYLYDEGEE EEVFNDEWGA AGGVAVATLN ALERSFLSAM DWRLYTDPRE
     IFEVLSWLES CVAEQQGRRR GWYTYTDLCV LLEQPTWQLA LGSLCQRLVK LSCLLAVAYV
     SSVALAVASV AVIHQSLGLS SSPSPGPPEL TLVSKSLVQP CVPAPVSQCL TNVSSCLEGS
     VDLPSLWGSL LAPLTPPLRP PPDPPAPPTP LHKCPLCQKF QRLPPNCRAC HTNQTVSIGP
     SRPLYHARGL APPWLWSPVA PPFLQPQQCS LFSVMELAHL KSVISPG