ACL10_HUMAN
ID ACL10_HUMAN Reviewed; 245 AA.
AC Q5JWF8; B9EH76;
DT 18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Actin-like protein 10;
GN Name=ACTL10; Synonyms=C20orf134;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11780052; DOI=10.1038/414865a;
RA Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 20.";
RL Nature 414:865-871(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; AL121906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471077; EAW76309.1; -; Genomic_DNA.
DR EMBL; BC137111; AAI37112.1; -; mRNA.
DR EMBL; BC137114; AAI37115.1; -; mRNA.
DR CCDS; CCDS33463.1; -.
DR RefSeq; NP_001019846.1; NM_001024675.1.
DR AlphaFoldDB; Q5JWF8; -.
DR SMR; Q5JWF8; -.
DR STRING; 9606.ENSP00000329647; -.
DR iPTMnet; Q5JWF8; -.
DR PhosphoSitePlus; Q5JWF8; -.
DR BioMuta; ACTL10; -.
DR DMDM; 74742586; -.
DR MassIVE; Q5JWF8; -.
DR MaxQB; Q5JWF8; -.
DR PaxDb; Q5JWF8; -.
DR PeptideAtlas; Q5JWF8; -.
DR PRIDE; Q5JWF8; -.
DR ProteomicsDB; 63387; -.
DR Antibodypedia; 57049; 13 antibodies from 2 providers.
DR DNASU; 170487; -.
DR Ensembl; ENST00000677665.1; ENSP00000504425.1; ENSG00000288649.2.
DR GeneID; 170487; -.
DR KEGG; hsa:170487; -.
DR MANE-Select; ENST00000677665.1; ENSP00000504425.1; NM_001024675.2; NP_001019846.1.
DR UCSC; uc002wzt.3; human.
DR CTD; 170487; -.
DR GeneCards; ACTL10; -.
DR HGNC; HGNC:16127; ACTL10.
DR HPA; ENSG00000182584; Tissue enriched (testis).
DR neXtProt; NX_Q5JWF8; -.
DR PharmGKB; PA25676; -.
DR VEuPathDB; HostDB:ENSG00000182584; -.
DR eggNOG; KOG0676; Eukaryota.
DR GeneTree; ENSGT00940000162922; -.
DR HOGENOM; CLU_027965_5_2_1; -.
DR InParanoid; Q5JWF8; -.
DR OrthoDB; 649708at2759; -.
DR PhylomeDB; Q5JWF8; -.
DR TreeFam; TF300361; -.
DR PathwayCommons; Q5JWF8; -.
DR SignaLink; Q5JWF8; -.
DR BioGRID-ORCS; 170487; 21 hits in 1063 CRISPR screens.
DR GenomeRNAi; 170487; -.
DR Pharos; Q5JWF8; Tdark.
DR PRO; PR:Q5JWF8; -.
DR Proteomes; UP000005640; Chromosome 20.
DR RNAct; Q5JWF8; protein.
DR Bgee; ENSG00000288649; Expressed in granulocyte and 85 other tissues.
DR Genevisible; Q5JWF8; HS.
DR GO; GO:0005869; C:dynactin complex; IBA:GO_Central.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..245
FT /note="Actin-like protein 10"
FT /id="PRO_0000232865"
SQ SEQUENCE 245 AA; 26751 MW; 06EC6260DF9CC2EE CRC64;
MASTALLALC STGAFSGLAV EAGAGVCHAT PIYAGHSWHQ ATFRLNVAGS TLSRYLRDLL
VAANPDLLQQ ALPRKAITHL KKRSCYVSLD FEGDLRDPAR HHPASFSVGN GCCVCLSSER
FRCPEPIFQP GLLGQAEQGL PALAFRALQK MPKTLRTRLA DTVVLAGGST LFPGFAERLD
KELEAQCRRH GYAALRPHLV AKHGRGMAVW TGGSMVASLH SFQRRWITRA MYQECGSRLL
YDVFN
