CNPD3_SYNP6
ID CNPD3_SYNP6 Reviewed; 255 AA.
AC P05675; P05677; Q5N3J3;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Probable cyclic nucleotide phosphodiesterase syc0937_d {ECO:0000250|UniProtKB:P9WP65};
DE EC=3.1.4.- {ECO:0000250|UniProtKB:P9WP65};
GN OrderedLocusNames=syc0937_d;
OS Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS nidulans).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX NCBI_TaxID=269084;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RA Kumano M., Tomioka N., Shinozaki K., Sugiura M.;
RT "Analysis of the promoter region in the rrnA operon from a blue-green alga,
RT Anacystis nidulans 6301.";
RL Mol. Gen. Genet. 202:173-178(1986).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT Synechococcus elongatus PCC 6301 chromosome: gene content and
RT organization.";
RL Photosyn. Res. 93:55-67(2007).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000250|UniProtKB:Q6XBH1};
CC Note=Binds 2 Fe(2+) ions per subunit. {ECO:0000250|UniProtKB:Q6XBH1};
CC -!- SIMILARITY: Belongs to the cyclic nucleotide phosphodiesterase class-
CC III family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA27241.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X03538; CAA27240.1; ALT_FRAME; Genomic_DNA.
DR EMBL; X03538; CAA27241.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AP008231; BAD79127.1; -; Genomic_DNA.
DR PIR; S10913; S10913.
DR PIR; S10914; S10914.
DR AlphaFoldDB; P05675; -.
DR SMR; P05675; -.
DR STRING; 269084.syc0937_d; -.
DR EnsemblBacteria; BAD79127; BAD79127; syc0937_d.
DR KEGG; syc:syc0937_d; -.
DR eggNOG; COG1409; Bacteria.
DR OMA; CAWLDQH; -.
DR Proteomes; UP000001175; Chromosome.
DR GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; SSF56300; 1.
PE 3: Inferred from homology;
KW Hydrolase; Iron; Metal-binding; Nucleotide-binding.
FT CHAIN 1..255
FT /note="Probable cyclic nucleotide phosphodiesterase
FT syc0937_d"
FT /id="PRO_0000066100"
FT BINDING 19
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 21
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0000250|UniProtKB:P9WP65"
FT BINDING 21
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 59
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0000250|UniProtKB:P9WP65"
FT BINDING 59
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 59
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 89..90
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0000250|UniProtKB:P9WP65"
FT BINDING 89
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 157
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 196
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT BINDING 198
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0000250|UniProtKB:P9WP65"
FT BINDING 198
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q6XBH1"
FT CONFLICT 44
FT /note="G -> A (in Ref. 1; CAA27241)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 255 AA; 28172 MW; 1290DCCF13D726E6 CRC64;
MVEDFAGDAM TLSIAQITDL HLLVDPQAAL RGCVTTPRAA AVFGNLKQRS PDLLLLSGDL
SEDGSPASYE RLRDWVEELG CPAIAIAGNH DQPERLTEIC GRSPFMGEPV YSIQGWRIIA
LDSYQPKRID GRLRGDQLDW LDQRLGEDSS PTLLMLHHPP VLIGVTKMDA IGLKDGPEFL
EVIAHHQQVR LVLSGHAHQA FIQGRGLTTF LGCPATAMQF DQPELPAGWR SLELEPDGSW
RSQIHWVDTD SIHFA
