CNPY1_MOUSE
ID CNPY1_MOUSE Reviewed; 94 AA.
AC Q4VAB4; Q8CBK9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Protein canopy homolog 1;
GN Name=Cnpy1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J; TISSUE=Cerebellum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Olfactory epithelium;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q4VAB4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q4VAB4-2; Sequence=VSP_030193;
CC -!- SIMILARITY: Belongs to the canopy family. {ECO:0000305}.
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DR EMBL; AK035828; BAC29203.1; -; mRNA.
DR EMBL; AK139155; BAE23904.1; -; mRNA.
DR EMBL; BC096464; AAH96464.1; -; mRNA.
DR CCDS; CCDS80237.1; -. [Q4VAB4-1]
DR RefSeq; NP_001297440.1; NM_001310511.1. [Q4VAB4-1]
DR RefSeq; NP_001297441.1; NM_001310512.1. [Q4VAB4-1]
DR AlphaFoldDB; Q4VAB4; -.
DR SMR; Q4VAB4; -.
DR STRING; 10090.ENSMUSP00000112773; -.
DR PRIDE; Q4VAB4; -.
DR Antibodypedia; 49629; 10 antibodies from 8 providers.
DR Ensembl; ENSMUST00000117098; ENSMUSP00000113956; ENSMUSG00000044681. [Q4VAB4-2]
DR Ensembl; ENSMUST00000118882; ENSMUSP00000113944; ENSMUSG00000044681. [Q4VAB4-1]
DR Ensembl; ENSMUST00000120068; ENSMUSP00000112773; ENSMUSG00000044681. [Q4VAB4-2]
DR GeneID; 269637; -.
DR KEGG; mmu:269637; -.
DR UCSC; uc008wtw.1; mouse. [Q4VAB4-1]
DR UCSC; uc008wtx.1; mouse. [Q4VAB4-2]
DR CTD; 285888; -.
DR MGI; MGI:2442451; Cnpy1.
DR VEuPathDB; HostDB:ENSMUSG00000044681; -.
DR eggNOG; KOG3782; Eukaryota.
DR GeneTree; ENSGT00940000161119; -.
DR HOGENOM; CLU_1558921_0_0_1; -.
DR InParanoid; Q4VAB4; -.
DR BioGRID-ORCS; 269637; 4 hits in 73 CRISPR screens.
DR PRO; PR:Q4VAB4; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q4VAB4; protein.
DR Bgee; ENSMUSG00000044681; Expressed in cerebellum lobe and 69 other tissues.
DR ExpressionAtlas; Q4VAB4; baseline and differential.
DR Genevisible; Q4VAB4; MM.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR InterPro; IPR042415; CNPY.
DR InterPro; IPR021852; DUF3456.
DR PANTHER; PTHR13341; PTHR13341; 1.
DR Pfam; PF11938; DUF3456; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..94
FT /note="Protein canopy homolog 1"
FT /id="PRO_0000314016"
FT VAR_SEQ 83..94
FT /note="DLCGTPTNSPEP -> GTVSDVTRAPSLTYQLQLSLAQLIHRVAWLSYCQPG
FT STQTSGDQTPMPERRATEPHARAFLMTFLLCLCFFVFVCFPKNVGLTLPLIFRAG (in
FT isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_030193"
SQ SEQUENCE 94 AA; 11249 MW; 6963F745C7C0F911 CRC64;
MRMNDYQLED DPVTKQKYFR RYAPRKGDKI YKEYKKFFFY SDAFRPLKFA CEAIIEKYED
EIFELIAQEA NHLADMLCNE KSDLCGTPTN SPEP
