ID   CNPY1_XENLA             Reviewed;         181 AA.
AC   Q5M7D4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Protein canopy homolog 1;
DE   Flags: Precursor;
GN   Name=cnpy1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an role in early embryonic development. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000255|PROSITE-
CC       ProRule:PRU10138}.
CC   -!- SIMILARITY: Belongs to the canopy family. {ECO:0000305}.
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DR   EMBL; BC088697; AAH88697.1; -; mRNA.
DR   RefSeq; NP_001088889.1; NM_001095420.1.
DR   AlphaFoldDB; Q5M7D4; -.
DR   SMR; Q5M7D4; -.
DR   DNASU; 496234; -.
DR   GeneID; 496234; -.
DR   KEGG; xla:496234; -.
DR   CTD; 496234; -.
DR   Xenbase; XB-GENE-981810; cnpy1.S.
DR   OMA; MAPWIIQ; -.
DR   Proteomes; UP000186698; Chromosome 6S.
DR   Bgee; 496234; Expressed in zone of skin and 19 other tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   InterPro; IPR042415; CNPY.
DR   InterPro; IPR021852; DUF3456.
DR   PANTHER; PTHR13341; PTHR13341; 1.
DR   Pfam; PF11938; DUF3456; 1.
DR   PROSITE; PS00014; ER_TARGET; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Disulfide bond; Endoplasmic reticulum;
KW   Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..181
FT                   /note="Protein canopy homolog 1"
FT                   /id="PRO_0000314014"
FT   DOMAIN          25..177
FT                   /note="Saposin B-type"
FT   MOTIF           178..181
FT                   /note="Prevents secretion from ER"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10138"
FT   DISULFID        29..173
FT                   /evidence="ECO:0000250"
FT   DISULFID        32..166
FT                   /evidence="ECO:0000250"
FT   DISULFID        87..139
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   181 AA;  20706 MW;  B2B8641C5413F924 CRC64;
     MAILLHFGVL ITAFLSSHVE GKRDPILYCG ACRALVDELL YEIRKVNPKK TVDVGSFRIS
     PDGKQEQNKV PFAKSELYLT DVLEEICEKM NDYGLYVDPT TQEKSYKRFA PRDNEGIGSV
     DFKNFQFNPE ESNSLKYACE RVVEEHEDEV LSVITKENDN LADKLCTEET GLCKEYLHNE
     L