CNR1_MAIZE
ID CNR1_MAIZE Reviewed; 191 AA.
AC B6TZ45; B4FTQ5;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Cell number regulator 1;
DE AltName: Full=ZmCNR01;
GN Name=CNR1;
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. B73;
RX PubMed=20400678; DOI=10.1105/tpc.109.073676;
RA Guo M., Rupe M.A., Dieter J.A., Zou J., Spielbauer D., Duncan K.E.,
RA Howard R.J., Hou Z., Simmons C.R.;
RT "Cell Number Regulator1 affects plant and organ size in maize: implications
RT for crop yield enhancement and heterosis.";
RL Plant Cell 22:1057-1073(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. B73;
RA Yu Y., Currie J., Lomeli R., Angelova A., Collura K., Wissotski M.,
RA Campos D., Kudrna D., Golser W., Ashely E., Haller K., Descour A.,
RA Fernandes J., Zuccolo A., Soderlund C., Walbot V.;
RT "Maize full-length cDNA project.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.-P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
CC -!- FUNCTION: Acts as a negative regulator of cell number.
CC {ECO:0000269|PubMed:20400678}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, coleoptiles, stalks and silks.
CC Detected in leaves, apical meristems, immature ears and pericarps.
CC Highest expression in coleoptiles and silks.
CC {ECO:0000269|PubMed:20400678}.
CC -!- SIMILARITY: Belongs to the cornifelin family. {ECO:0000305}.
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DR EMBL; HM008653; ADI48415.1; -; mRNA.
DR EMBL; BT040493; ACF85498.1; -; mRNA.
DR EMBL; EU970260; ACG42378.1; -; mRNA.
DR RefSeq; NP_001151323.1; NM_001157851.1.
DR AlphaFoldDB; B6TZ45; -.
DR STRING; 4577.GRMZM2G015941_P01; -.
DR PaxDb; B6TZ45; -.
DR GeneID; 100284956; -.
DR eggNOG; ENOG502RZ8E; Eukaryota.
DR OrthoDB; 1354725at2759; -.
DR Proteomes; UP000007305; Unplaced.
DR ExpressionAtlas; B6TZ45; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IMP:UniProtKB.
DR InterPro; IPR006461; PLAC_motif_containing.
DR PANTHER; PTHR15907; PTHR15907; 1.
DR Pfam; PF04749; PLAC8; 1.
DR TIGRFAMs; TIGR01571; A_thal_Cys_rich; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..191
FT /note="Cell number regulator 1"
FT /id="PRO_0000407729"
FT TRANSMEM 91..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 13..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 29..30
FT /note="Missing (in Ref. 2; ACF85498)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 191 AA; 20460 MW; CA28F7C0238D463D CRC64;
MYPSAPPDAY NKFSAGAPPT APPPPAAYHQ QQQQHGANMD TSRPGGGLRK WSTGLFHCMD
DPGNCLITCL CPCVTFGQVA DIVDKGTCPC IASGLVYGLI CASTGMGCLY SCLYRSKLRA
EYDLDEGECP DILVHCCCEH LALCQEYREL KNRGFDLGIG WEANMDRQRR GVAGGGAVMG
APPAIPLGMI R
