ID   CNRP1_BOVIN             Reviewed;         164 AA.
AC   Q17QM9;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=CB1 cannabinoid receptor-interacting protein 1;
DE            Short=CRIP-1;
GN   Name=CNRIP1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Basal ganglia;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Suppresses cannabinoid receptor CNR1-mediated tonic
CC       inhibition of voltage-gated calcium channels. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the cannabinoid receptor CNR1 (via C-terminus).
CC       Does not interact with cannabinoid receptor CNR2 (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CNRIP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC118266; AAI18267.1; -; mRNA.
DR   RefSeq; NP_001069651.1; NM_001076183.1.
DR   AlphaFoldDB; Q17QM9; -.
DR   SMR; Q17QM9; -.
DR   STRING; 9913.ENSBTAP00000001847; -.
DR   BindingDB; Q17QM9; -.
DR   PaxDb; Q17QM9; -.
DR   Ensembl; ENSBTAT00000001847; ENSBTAP00000001847; ENSBTAG00000001408.
DR   GeneID; 539715; -.
DR   KEGG; bta:539715; -.
DR   CTD; 25927; -.
DR   VEuPathDB; HostDB:ENSBTAG00000001408; -.
DR   VGNC; VGNC:27531; CNRIP1.
DR   eggNOG; ENOG502QTXE; Eukaryota.
DR   GeneTree; ENSGT00390000004284; -.
DR   HOGENOM; CLU_110298_0_0_1; -.
DR   InParanoid; Q17QM9; -.
DR   OMA; YCKMETS; -.
DR   OrthoDB; 1364162at2759; -.
DR   TreeFam; TF332485; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000001408; Expressed in Ammon's horn and 107 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0031718; F:type 1 cannabinoid receptor binding; IBA:GO_Central.
DR   GO; GO:2000272; P:negative regulation of signaling receptor activity; IBA:GO_Central.
DR   InterPro; IPR029204; CNRIP1.
DR   PANTHER; PTHR31952; PTHR31952; 1.
DR   Pfam; PF15043; CNRIP1; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..164
FT                   /note="CB1 cannabinoid receptor-interacting protein 1"
FT                   /id="PRO_0000265093"
SQ   SEQUENCE   164 AA;  18664 MW;  5F28BDC7FBED82EE CRC64;
     MGDLPGLVRL SIALRIQPND GPVFYKVDGQ RFGQNRTIKL LTGSSYKVEV KIKPTTLQVE
     NISIGGVVVP LELKSKEPDG DRIVYTGTYD TEGVAPTKSG ERQPIQITMP FTDIGTFETM
     WQVKFYNYHK RDHCQWGSPF SVIEYECKPN ETRSLMWVNK ESFL