CNRP1_MACFA
ID CNRP1_MACFA Reviewed; 164 AA.
AC Q9GKT6;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 35.
DE RecName: Full=CB1 cannabinoid receptor-interacting protein 1;
DE Short=CRIP-1;
GN Name=CNRIP1; ORFNames=QccE-20325;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RA Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirai M., Terao K.,
RA Suzuki Y., Sugano S., Hashimoto K.;
RT "Isolation of full-length cDNA clones from macaque brain cDNA libraries.";
RL Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Suppresses cannabinoid receptor CNR1-mediated tonic
CC inhibition of voltage-gated calcium channels. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the cannabinoid receptor CNR1 (via C-terminus).
CC Does not interact with cannabinoid receptor CNR2 (By similarity).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CNRIP family. {ECO:0000305}.
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DR EMBL; AB052144; BAB18998.1; -; mRNA.
DR AlphaFoldDB; Q9GKT6; -.
DR SMR; Q9GKT6; -.
DR STRING; 9541.XP_005575764.1; -.
DR eggNOG; ENOG502QTXE; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR InterPro; IPR029204; CNRIP1.
DR PANTHER; PTHR31952; PTHR31952; 1.
DR Pfam; PF15043; CNRIP1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..164
FT /note="CB1 cannabinoid receptor-interacting protein 1"
FT /id="PRO_0000089361"
SQ SEQUENCE 164 AA; 18618 MW; 5E8432C125F4FF1E CRC64;
MGDLPGLVRL SIALRIQPND GPVFYKVDGQ RFGQNRTIKL LTGSSYKVEV KIKPSTLQVE
NISIGGVLVP LELKSKEPDG DRVVYTGTYD TEGVTPTKSG ERQPIQITMP FADIGTFETV
WQVKFYNYHK RDHCQWGSPF SVIEYECKPN ETRSLMWVNK ESFL