ID   CNU_ECOL5               Reviewed;          71 AA.
AC   Q0THK2;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=OriC-binding nucleoid-associated protein;
DE   AltName: Full=H-NS/StpA-binding protein 2;
DE   AltName: Full=Transcription modulator YdgT;
GN   Name=cnu; Synonyms=ydgT; OrderedLocusNames=ECP_1570;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- FUNCTION: Modifies the set of genes regulated by H-NS; Hha and cnu
CC       (YdgT) increase the number of genes bound by H-NS/StpA and may also
CC       modulate the oligomerization of the H-NS/StpA-complex on DNA. The
CC       complex formed with H-NS binds to the specific 26-bp cnb site in the
CC       origin of replication oriC. {ECO:0000250|UniProtKB:P64467}.
CC   -!- SUBUNIT: Forms complexes with both H-NS and StpA.
CC       {ECO:0000250|UniProtKB:P64467}.
CC   -!- SIMILARITY: Belongs to the Hha/YmoA/Cnu family. {ECO:0000305}.
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DR   EMBL; CP000247; ABG69577.1; -; Genomic_DNA.
DR   RefSeq; WP_000217950.1; NC_008253.1.
DR   AlphaFoldDB; Q0THK2; -.
DR   SMR; Q0THK2; -.
DR   STRING; 362663.ECP_1570; -.
DR   EnsemblBacteria; ABG69577; ABG69577; ECP_1570.
DR   GeneID; 66674483; -.
DR   KEGG; ecp:ECP_1570; -.
DR   HOGENOM; CLU_190629_0_0_6; -.
DR   OMA; PKSVWHF; -.
DR   Proteomes; UP000009182; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1280.40; -; 1.
DR   InterPro; IPR007985; Hemolysn_expr_modulating_HHA.
DR   InterPro; IPR036666; HHA_sf.
DR   Pfam; PF05321; HHA; 1.
DR   SUPFAM; SSF68989; SSF68989; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..71
FT                   /note="OriC-binding nucleoid-associated protein"
FT                   /id="PRO_0000305050"
FT   SITE            44
FT                   /note="Interacts with H-NS"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   71 AA;  8417 MW;  CE9FF2E890E78219 CRC64;
     MTVQDYLLKF RKISSLESLE KLYDHLNYTL TDDQELINMY RAADHRRAEL VSGGRLFDLG
     QVPKSVWHYV Q