ID   CNU_ECOUT               Reviewed;          71 AA.
AC   Q1RBH1;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=OriC-binding nucleoid-associated protein;
DE   AltName: Full=H-NS/StpA-binding protein 2;
DE   AltName: Full=Transcription modulator YdgT;
GN   Name=cnu; Synonyms=ydgT; OrderedLocusNames=UTI89_C1815;
OS   Escherichia coli (strain UTI89 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=364106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UTI89 / UPEC;
RX   PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA   Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA   Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA   Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA   Gordon J.I.;
RT   "Identification of genes subject to positive selection in uropathogenic
RT   strains of Escherichia coli: a comparative genomics approach.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC   -!- FUNCTION: Modifies the set of genes regulated by H-NS; Hha and cnu
CC       (YdgT) increase the number of genes bound by H-NS/StpA and may also
CC       modulate the oligomerization of the H-NS/StpA-complex on DNA. The
CC       complex formed with H-NS binds to the specific 26-bp cnb site in the
CC       origin of replication oriC. {ECO:0000250|UniProtKB:P64467}.
CC   -!- SUBUNIT: Forms complexes with both H-NS and StpA.
CC       {ECO:0000250|UniProtKB:P64467}.
CC   -!- SIMILARITY: Belongs to the Hha/YmoA/Cnu family. {ECO:0000305}.
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DR   EMBL; CP000243; ABE07293.1; -; Genomic_DNA.
DR   RefSeq; WP_000217950.1; NC_007946.1.
DR   AlphaFoldDB; Q1RBH1; -.
DR   SMR; Q1RBH1; -.
DR   EnsemblBacteria; ABE07293; ABE07293; UTI89_C1815.
DR   GeneID; 66674483; -.
DR   KEGG; eci:UTI89_C1815; -.
DR   HOGENOM; CLU_190629_0_0_6; -.
DR   OMA; PKSVWHF; -.
DR   Proteomes; UP000001952; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1280.40; -; 1.
DR   InterPro; IPR007985; Hemolysn_expr_modulating_HHA.
DR   InterPro; IPR036666; HHA_sf.
DR   Pfam; PF05321; HHA; 1.
DR   SUPFAM; SSF68989; SSF68989; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..71
FT                   /note="OriC-binding nucleoid-associated protein"
FT                   /id="PRO_0000305049"
FT   SITE            44
FT                   /note="Interacts with H-NS"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   71 AA;  8417 MW;  CE9FF2E890E78219 CRC64;
     MTVQDYLLKF RKISSLESLE KLYDHLNYTL TDDQELINMY RAADHRRAEL VSGGRLFDLG
     QVPKSVWHYV Q