CO032_HUMAN
ID CO032_HUMAN Reviewed; 178 AA.
AC Q32M92; C5HTZ8; Q96M45;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Uncharacterized protein C15orf32;
GN Name=C15orf32;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RG NHLBI resequencing and genotyping service (RS&G);
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q32M92-2; Q96CV9: OPTN; NbExp=3; IntAct=EBI-25911375, EBI-748974;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q32M92-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q32M92-2; Sequence=VSP_019516;
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DR EMBL; AK057393; BAB71467.1; -; mRNA.
DR EMBL; FJ515837; ACS13729.1; -; Genomic_DNA.
DR EMBL; CH471101; EAX02151.1; -; Genomic_DNA.
DR EMBL; BC109252; AAI09253.1; -; mRNA.
DR EMBL; BC109253; AAI09254.1; -; mRNA.
DR RefSeq; NP_001288035.1; NM_001301106.1.
DR RefSeq; NP_694585.1; NM_153040.2.
DR AlphaFoldDB; Q32M92; -.
DR BioGRID; 126949; 13.
DR IntAct; Q32M92; 1.
DR STRING; 9606.ENSP00000330267; -.
DR iPTMnet; Q32M92; -.
DR PhosphoSitePlus; Q32M92; -.
DR BioMuta; HGNC:26549; -.
DR DMDM; 109822357; -.
DR MaxQB; Q32M92; -.
DR PaxDb; Q32M92; -.
DR PeptideAtlas; Q32M92; -.
DR PRIDE; Q32M92; -.
DR ProteomicsDB; 61598; -. [Q32M92-1]
DR ProteomicsDB; 61599; -. [Q32M92-2]
DR GeneCards; C15orf32; -.
DR HGNC; HGNC:26549; C15orf32.
DR neXtProt; NX_Q32M92; -.
DR PharmGKB; PA142672268; -.
DR eggNOG; ENOG502TDHB; Eukaryota.
DR InParanoid; Q32M92; -.
DR PhylomeDB; Q32M92; -.
DR TreeFam; TF342159; -.
DR PathwayCommons; Q32M92; -.
DR SignaLink; Q32M92; -.
DR BioGRID-ORCS; 145858; 16 hits in 1048 CRISPR screens.
DR ChiTaRS; C15orf32; human.
DR GenomeRNAi; 145858; -.
DR Pharos; Q32M92; Tdark.
DR PRO; PR:Q32M92; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q32M92; protein.
PE 1: Evidence at protein level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..178
FT /note="Uncharacterized protein C15orf32"
FT /id="PRO_0000244097"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 166..178
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_019516"
FT VARIANT 17
FT /note="A -> T (in dbSNP:rs1455773)"
FT /id="VAR_050884"
SQ SEQUENCE 178 AA; 20262 MW; 15744DB57F544812 CRC64;
MNKRTSVDAS KEDLHPADPQ SGEGVPPNRK NTKTSPRGEG TAPPFSARPC VWTLCEMLSI
LALVGVLHPF YRSNNQVYQK LKTHLRCQSS RVDGLMLKPT LLTPSQLKSP EGHLILPTFN
HLVIRHILDP KQIFCVADVC TDCKFNCGSI ERHQKRHLMR VSQDWEHLIR YRNQICLS
