CO040_MOUSE
ID CO040_MOUSE Reviewed; 126 AA.
AC Q9CRC3; Q8K3A3;
DT 11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=UPF0235 protein C15orf40 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo, and Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, and Liver;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the UPF0235 family. {ECO:0000305}.
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DR EMBL; AK019261; BAB31634.1; -; mRNA.
DR EMBL; AK014163; BAB29184.1; -; mRNA.
DR EMBL; AK018003; BAB31031.1; -; mRNA.
DR EMBL; BC027500; AAH27500.1; -; mRNA.
DR CCDS; CCDS40010.1; -.
DR RefSeq; NP_080353.1; NM_026077.3.
DR RefSeq; XP_011249199.1; XM_011250897.2.
DR AlphaFoldDB; Q9CRC3; -.
DR SMR; Q9CRC3; -.
DR STRING; 10090.ENSMUSP00000026092; -.
DR PhosphoSitePlus; Q9CRC3; -.
DR EPD; Q9CRC3; -.
DR MaxQB; Q9CRC3; -.
DR PaxDb; Q9CRC3; -.
DR PRIDE; Q9CRC3; -.
DR Antibodypedia; 49874; 172 antibodies from 18 providers.
DR DNASU; 67290; -.
DR Ensembl; ENSMUST00000026092; ENSMUSP00000026092; ENSMUSG00000025102.
DR GeneID; 67290; -.
DR KEGG; mmu:67290; -.
DR UCSC; uc009icm.1; mouse.
DR MGI; MGI:1914540; 3110040N11Rik.
DR VEuPathDB; HostDB:ENSMUSG00000025102; -.
DR eggNOG; KOG3276; Eukaryota.
DR GeneTree; ENSGT00390000012420; -.
DR HOGENOM; CLU_130694_2_0_1; -.
DR InParanoid; Q9CRC3; -.
DR OMA; PGAKQNG; -.
DR OrthoDB; 1546648at2759; -.
DR PhylomeDB; Q9CRC3; -.
DR TreeFam; TF313882; -.
DR BioGRID-ORCS; 67290; 0 hits in 70 CRISPR screens.
DR PRO; PR:Q9CRC3; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q9CRC3; protein.
DR Bgee; ENSMUSG00000025102; Expressed in right kidney and 209 other tissues.
DR ExpressionAtlas; Q9CRC3; baseline and differential.
DR Genevisible; Q9CRC3; MM.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR Gene3D; 3.30.1200.10; -; 1.
DR HAMAP; MF_00634; UPF0235; 1.
DR InterPro; IPR003746; DUF167.
DR InterPro; IPR036591; YggU-like_sf.
DR PANTHER; PTHR13420; PTHR13420; 1.
DR Pfam; PF02594; DUF167; 1.
DR SMART; SM01152; DUF167; 1.
DR SUPFAM; SSF69786; SSF69786; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..126
FT /note="UPF0235 protein C15orf40 homolog"
FT /id="PRO_0000139476"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 89
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8WUR7"
FT CONFLICT 69
FT /note="E -> Q (in Ref. 2; AAH27500)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 126 AA; 13189 MW; 03373D591B1284A1 CRC64;
MPKKAGATSK GKNQTKEPET APPAAGPVAT DPKGFVTIAI HAKPGSRQNA VTDLSTEAVG
VAIAAPPSEG EANAELCRYL SKVLDLRKSD VVLDKGGKSR EKVVKLLAST TPEEVLEKLK
TEAEKK
