ID   CO145_CAEBR             Reviewed;         561 AA.
AC   A8XV37;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-MAY-2016, sequence version 2.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Putative cuticle collagen 145 {ECO:0000250|UniProtKB:Q17459};
DE   Flags: Precursor;
GN   Name=col-145 {ECO:0000312|EMBL:CAP36504.2}; ORFNames=CBG19217;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP36504.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAP36504.2};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Nematode cuticles are composed largely of collagen-like
CC       proteins. The cuticle functions both as an exoskeleton and as a barrier
CC       to protect the worm from its environment (By similarity).
CC       {ECO:0000250|UniProtKB:Q17459}.
CC   -!- SUBUNIT: Collagen polypeptide chains are complexed within the cuticle
CC       by disulfide bonds and other types of covalent cross-links.
CC       {ECO:0000250|UniProtKB:Q17459}.
CC   -!- SIMILARITY: Belongs to the cuticular collagen family. {ECO:0000255}.
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DR   EMBL; HE601047; CAP36504.2; -; Genomic_DNA.
DR   AlphaFoldDB; A8XV37; -.
DR   SMR; A8XV37; -.
DR   STRING; 6238.CBG19217; -.
DR   WormBase; CBG19217; CBP43255; WBGene00038475; Cbr-col-145.
DR   eggNOG; KOG3544; Eukaryota.
DR   HOGENOM; CLU_001074_4_3_1; -.
DR   InParanoid; A8XV37; -.
DR   OMA; ATEGFAY; -.
DR   OrthoDB; 1751568at2759; -.
DR   Proteomes; UP000008549; Chromosome V.
DR   GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   InterPro; IPR002486; Col_cuticle_N.
DR   InterPro; IPR008160; Collagen.
DR   Pfam; PF01484; Col_cuticle_N; 1.
DR   Pfam; PF01391; Collagen; 1.
DR   SMART; SM01088; Col_cuticle_N; 1.
PE   3: Inferred from homology;
KW   Collagen; Cuticle; Disulfide bond; Reference proteome; Repeat; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..561
FT                   /note="Putative cuticle collagen 145"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000351211"
FT   DOMAIN          485..543
FT                   /note="Collagen-like"
FT                   /evidence="ECO:0000255"
FT   REGION          100..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          102..127
FT                   /note="Triple-helical region"
FT                   /evidence="ECO:0000255"
FT   REGION          148..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          153..276
FT                   /note="Triple-helical region"
FT                   /evidence="ECO:0000255"
FT   REGION          367..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          413..544
FT                   /note="Triple-helical region"
FT                   /evidence="ECO:0000255"
FT   REGION          422..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..119
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        153..167
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..386
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   561 AA;  54598 MW;  8B4FAA42C188AB8B CRC64;
     MEKILVTLST GAASIAVLAV LFTIPSLYNT INEVHDEVLD GVSVFRVETD SAWTEMMDIQ
     ITVTPPTKPR VNPFNSIFRQ KRQTFSGLPA WCQCEPTKPT CPPGPPGPPG QPGQPGTPGA
     PGPKGEDNTS TYAPITCAPV SQDCVKCPQG PAGPEGPAGP AGPAGPDGQP GAPGNAGNPG
     SDGQPGAPGD DGQPGAPGQD GQPGAPGQDG QRGSGAPGAP GAPGNAGPAG PAGQDGAPGQ
     DGQPGPAGPA GQDGAPGNAG SDGQPGAPGG PGLPGNDAAY CACPHGEDSC DHLYRSCLPR
     CFGEVLDGVS VFRVETDSAW TEMMDIQVTV TPPTKPRVNP FNSVFRQKRQ TFSGLPAWCQ
     CEPTKPTCPP GPPGPPGQPG QPGTPGAPGP KGEDNTATYA PITCAPVSQD CVKCPQGPAG
     PTGPAGLAGP AGPDGQPGFP GQRGNDGFPG APGAPGDNGQ PGAPGQDGFP GQPGADGQRG
     SGAPGAPGAP GNAGPAGPAG QDGFPGQDGQ PGPAGPAGQD GFPGNAGSDG QPGAPGGPGL
     PGNDAAYCAC PPRSAVFLSR H