ID   COA3_ASHGO              Reviewed;          89 AA.
AC   Q758B5;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
GN   Name=COA3; OrderedLocusNames=AEL163C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC       assembly intermediates or COA complexes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
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DR   EMBL; AE016818; AAS52522.1; -; Genomic_DNA.
DR   RefSeq; NP_984698.1; NM_210051.1.
DR   AlphaFoldDB; Q758B5; -.
DR   SMR; Q758B5; -.
DR   STRING; 33169.AAS52522; -.
DR   EnsemblFungi; AAS52522; AAS52522; AGOS_AEL163C.
DR   GeneID; 4620883; -.
DR   KEGG; ago:AGOS_AEL163C; -.
DR   eggNOG; ENOG502S440; Eukaryota.
DR   HOGENOM; CLU_153999_0_0_1; -.
DR   InParanoid; Q758B5; -.
DR   OMA; WKMTPAM; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IBA:GO_Central.
DR   InterPro; IPR041752; Coa3.
DR   PANTHER; PTHR15642; PTHR15642; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..89
FT                   /note="Cytochrome c oxidase assembly factor 3,
FT                   mitochondrial"
FT                   /id="PRO_0000405436"
FT   TOPO_DOM        1..28
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        29..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        52..89
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   89 AA;  10490 MW;  59B7E530A5AAF8D1 CRC64;
     MLEPSRYQDP RTWKMTPAMI RARRPYIRGN LFGLVTLLGV AGGIYVYTYR ALHKDDDFAD
     VPIPPVSEEE LRQLRQEYEL HKKQRAAER