ID   COA3_CANAW              Reviewed;          88 AA.
AC   C4YTL7;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
GN   Name=COA3; ORFNames=CAWG_05512;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC       assembly intermediates or COA complexes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
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DR   EMBL; CM000313; EEQ46958.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YTL7; -.
DR   STRING; 5476.C4YTL7; -.
DR   EnsemblFungi; EEQ46958; EEQ46958; CAWG_05512.
DR   VEuPathDB; FungiDB:CAWG_05512; -.
DR   HOGENOM; CLU_153999_0_0_1; -.
DR   OMA; WKMTPAM; -.
DR   Proteomes; UP000001429; Chromosome 7.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:InterPro.
DR   InterPro; IPR041752; Coa3.
DR   PANTHER; PTHR15642; PTHR15642; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..88
FT                   /note="Cytochrome c oxidase assembly factor 3,
FT                   mitochondrial"
FT                   /id="PRO_0000405437"
FT   TOPO_DOM        1..32
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        33..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        56..88
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   88 AA;  10135 MW;  CB2BE255F5CF9DBC CRC64;
     MGKLVGAPKG HDRYRDPKTH QITPALYRVR APFFWRNTIA LFAVSSIPLA VYLYTFKKMG
     DDDLGDIPIP PISDEELQKL KLEYENQK