COA3_CANDC
ID COA3_CANDC Reviewed; 88 AA.
AC B9WK46;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
GN Name=COA3; ORFNames=CD36_71440;
OS Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS NRRL Y-17841) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=573826;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841;
RX PubMed=19745113; DOI=10.1101/gr.097501.109;
RA Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT Candida albicans.";
RL Genome Res. 19:2231-2244(2009).
CC -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC assembly intermediates or COA complexes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass
CC membrane protein.
CC -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FM992694; CAX40697.1; -; Genomic_DNA.
DR RefSeq; XP_002421363.1; XM_002421318.1.
DR AlphaFoldDB; B9WK46; -.
DR STRING; 42374.XP_002421363.1; -.
DR EnsemblFungi; CAX40697; CAX40697; CD36_71440.
DR GeneID; 8049330; -.
DR KEGG; cdu:CD36_71440; -.
DR CGD; CAL0000159215; Cd36_71440.
DR VEuPathDB; FungiDB:CD36_71440; -.
DR eggNOG; ENOG502S440; Eukaryota.
DR HOGENOM; CLU_153999_0_0_1; -.
DR OrthoDB; 1518220at2759; -.
DR Proteomes; UP000002605; Chromosome 7.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:InterPro.
DR InterPro; IPR041752; Coa3.
DR PANTHER; PTHR15642; PTHR15642; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..88
FT /note="Cytochrome c oxidase assembly factor 3,
FT mitochondrial"
FT /id="PRO_0000405438"
FT TOPO_DOM 1..32
FT /note="Mitochondrial matrix"
FT /evidence="ECO:0000250"
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 56..88
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000250"
SQ SEQUENCE 88 AA; 10135 MW; CB2BE255F5CF9DBC CRC64;
MGKLVGAPKG HDRYRDPKTH QITPALYRVR APFFWRNTIA LFAVSSIPLA VYLYTFKKMG
DDDLGDIPIP PISDEELQKL KLEYENQK