ID   COA3_KOMPG              Reviewed;          85 AA.
AC   C4R127;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
GN   Name=COA3; OrderedLocusNames=PAS_chr2-1_0565;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC       assembly intermediates or COA complexes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
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DR   EMBL; FN392320; CAY69201.1; -; Genomic_DNA.
DR   RefSeq; XP_002491481.1; XM_002491436.1.
DR   AlphaFoldDB; C4R127; -.
DR   SMR; C4R127; -.
DR   STRING; 644223.C4R127; -.
DR   EnsemblFungi; CAY69201; CAY69201; PAS_chr2-1_0565.
DR   GeneID; 8198932; -.
DR   KEGG; ppa:PAS_chr2-1_0565; -.
DR   eggNOG; ENOG502S440; Eukaryota.
DR   HOGENOM; CLU_153999_0_0_1; -.
DR   InParanoid; C4R127; -.
DR   OMA; WKMTPAM; -.
DR   Proteomes; UP000000314; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:InterPro.
DR   InterPro; IPR041752; Coa3.
DR   PANTHER; PTHR15642; PTHR15642; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..85
FT                   /note="Cytochrome c oxidase assembly factor 3,
FT                   mitochondrial"
FT                   /id="PRO_0000405445"
FT   TOPO_DOM        1..25
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        26..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        49..85
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   85 AA;  10144 MW;  17981B20FDD882A7 CRC64;
     MAQPDKYYNK YTYQMSPAML RARRPYFWKN MGAFGILGGI SLSVYLYTYN FLMQDDFENI
     PIPPIKDEDL AALRREYEEK KQLSK