ID   COA3_SCHPO              Reviewed;          69 AA.
AC   G2TRJ9;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2011, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
DE   AltName: Full=Transcripts altered in meiosis protein 3;
GN   Name=coa3; Synonyms=tam3; ORFNames=SPAC1B3.21;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   IDENTIFICATION, AND INDUCTION.
RX   PubMed=21270388; DOI=10.1534/genetics.110.123497;
RA   Bitton D.A., Wood V., Scutt P.J., Grallert A., Yates T., Smith D.L.,
RA   Hagan I.M., Miller C.J.;
RT   "Augmented annotation of the Schizosaccharomyces pombe genome reveals
RT   additional genes required for growth and viability.";
RL   Genetics 187:1207-1217(2011).
CC   -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC       assembly intermediates or COA complexes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
CC   -!- INDUCTION: Differentially expressed during meiosis.
CC       {ECO:0000269|PubMed:21270388}.
CC   -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
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DR   EMBL; CU329670; CCD31342.1; -; Genomic_DNA.
DR   RefSeq; XP_004001797.1; XM_004001748.1.
DR   AlphaFoldDB; G2TRJ9; -.
DR   SMR; G2TRJ9; -.
DR   STRING; 4896.SPAC1B3.21.1; -.
DR   MaxQB; G2TRJ9; -.
DR   PaxDb; G2TRJ9; -.
DR   EnsemblFungi; SPAC1B3.21.1; SPAC1B3.21.1:pep; SPAC1B3.21.
DR   PomBase; SPAC1B3.21; coa3.
DR   VEuPathDB; FungiDB:SPAC1B3.21; -.
DR   HOGENOM; CLU_202744_0_0_1; -.
DR   InParanoid; G2TRJ9; -.
DR   OMA; RVHEDTF; -.
DR   PRO; PR:G2TRJ9; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; ISO:PomBase.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; ISO:PomBase.
DR   InterPro; IPR041752; Coa3.
DR   InterPro; IPR018628; Coa3_cc.
DR   PANTHER; PTHR15642; PTHR15642; 1.
DR   Pfam; PF09813; Coiled-coil_56; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..69
FT                   /note="Cytochrome c oxidase assembly factor 3,
FT                   mitochondrial"
FT                   /id="PRO_0000416512"
FT   TOPO_DOM        1..19
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        43..69
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   69 AA;  7883 MW;  A5A7BFA649381114 CRC64;
     MNQGNQAFEN ARKPFRRANL ITALGLGAFA FATFAYSVYR VHEDTFEDVV MTPELEKKIA
     EDRDLSKKN