ID   COA3_YARLI              Reviewed;         106 AA.
AC   Q6CHT7;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
GN   Name=COA3; OrderedLocusNames=YALI0A05137g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC       assembly intermediates or COA complexes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
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DR   EMBL; CR382127; CAG83699.1; -; Genomic_DNA.
DR   RefSeq; XP_499774.1; XM_499774.1.
DR   AlphaFoldDB; Q6CHT7; -.
DR   SMR; Q6CHT7; -.
DR   STRING; 4952.CAG83699; -.
DR   EnsemblFungi; CAG83699; CAG83699; YALI0_A05137g.
DR   GeneID; 2905827; -.
DR   KEGG; yli:YALI0A05137g; -.
DR   VEuPathDB; FungiDB:YALI0_A05137g; -.
DR   HOGENOM; CLU_153999_0_0_1; -.
DR   InParanoid; Q6CHT7; -.
DR   OMA; NPKTHEM; -.
DR   Proteomes; UP000001300; Chromosome A.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IBA:GO_Central.
DR   InterPro; IPR041752; Coa3.
DR   PANTHER; PTHR15642; PTHR15642; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..106
FT                   /note="Cytochrome c oxidase assembly factor 3,
FT                   mitochondrial"
FT                   /id="PRO_0000405452"
FT   TOPO_DOM        1..48
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        49..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        72..106
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250"
FT   REGION          84..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   106 AA;  11965 MW;  EE72D33207D7954F CRC64;
     MSQDPHNGKG TFEVHKQPQP GLKVFRKGKY IDPKTFQMSP ALIRARRPFF VRNMLALAGL
     TGFVAGIYGY TMYSLRTDDF GDVPIPPLDP EEIKKLQSKY SDDSKA