COA3_ZYGRC
ID COA3_ZYGRC Reviewed; 87 AA.
AC C5E1G5;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 49.
DE RecName: Full=Cytochrome c oxidase assembly factor 3, mitochondrial;
GN Name=COA3; OrderedLocusNames=ZYRO0G20790g;
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Required for assembly of cytochrome c oxidase (complex IV).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of 250-400 kDa complexes called cytochrome oxidase
CC assembly intermediates or COA complexes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass
CC membrane protein.
CC -!- SIMILARITY: Belongs to the COA3 family. {ECO:0000305}.
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DR EMBL; CU928179; CAR29949.1; -; Genomic_DNA.
DR RefSeq; XP_002498882.1; XM_002498837.1.
DR AlphaFoldDB; C5E1G5; -.
DR STRING; 559307.C5E1G5; -.
DR EnsemblFungi; CAR29949; CAR29949; ZYRO0G20790g.
DR GeneID; 8206716; -.
DR KEGG; zro:ZYRO0G20790g; -.
DR HOGENOM; CLU_153999_0_0_1; -.
DR InParanoid; C5E1G5; -.
DR Proteomes; UP000008536; Chromosome G.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:InterPro.
DR InterPro; IPR041752; Coa3.
DR PANTHER; PTHR15642; PTHR15642; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..87
FT /note="Cytochrome c oxidase assembly factor 3,
FT mitochondrial"
FT /id="PRO_0000405453"
FT TOPO_DOM 1..30
FT /note="Mitochondrial matrix"
FT /evidence="ECO:0000250"
FT TRANSMEM 31..53
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 54..87
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000250"
SQ SEQUENCE 87 AA; 10283 MW; 476B9652DD02EDC4 CRC64;
MVLDPSRYQD HRTWKMTPGL IRARQPFFKK NMIGLAILAG VSAGIYTYTY SFLHKDNDFA
DVPIPPIDEK ELEKLKKEYE QHKQERQ