ID   COA8_CAEBR              Reviewed;         142 AA.
AC   A8WJ42;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=COA8 family protein CBG23705, mitochondrial {ECO:0000305};
DE            Short=COA8 {ECO:0000305};
DE   AltName: Full=APOPT family protein CBG23705, mitochondrial;
DE   Flags: Precursor;
GN   ORFNames=CBG23705;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: May be required for cytochrome c complex (COX) assembly and
CC       function, COX being the terminal component of the mitochondrial
CC       respiratory chain. {ECO:0000250|UniProtKB:Q96IL0}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9CQW7}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q96IL0}; Matrix side
CC       {ECO:0000250|UniProtKB:Q96IL0}.
CC   -!- SIMILARITY: Belongs to the COA8 family. {ECO:0000305}.
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DR   EMBL; HE601102; CAP20486.1; -; Genomic_DNA.
DR   RefSeq; XP_002638651.1; XM_002638605.1.
DR   AlphaFoldDB; A8WJ42; -.
DR   SMR; A8WJ42; -.
DR   STRING; 6238.CBG23705; -.
DR   EnsemblMetazoa; CBG23705.1; CBG23705.1; WBGene00041989.
DR   GeneID; 8580648; -.
DR   KEGG; cbr:CBG_23705; -.
DR   CTD; 8580648; -.
DR   WormBase; CBG23705; CBP13191; WBGene00041989; -.
DR   eggNOG; KOG4094; Eukaryota.
DR   HOGENOM; CLU_118274_0_1_1; -.
DR   InParanoid; A8WJ42; -.
DR   OMA; FNYNIAW; -.
DR   OrthoDB; 1410150at2759; -.
DR   Proteomes; UP000008549; Chromosome V.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:InterPro.
DR   InterPro; IPR018796; COA8.
DR   PANTHER; PTHR31107; PTHR31107; 1.
DR   Pfam; PF10231; DUF2315; 1.
PE   3: Inferred from homology;
KW   Apoptosis; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..142
FT                   /note="COA8 family protein CBG23705, mitochondrial"
FT                   /id="PRO_0000353111"
SQ   SEQUENCE   142 AA;  17390 MW;  5020F8791EE059FC CRC64;
     MSSLSSSSSN VRMDRRFDWV GPPDSVSKIR KIMLRRVDNE SELERQYRAA REELNQWNSD
     FWAEHNQLFD RQKSEFVEKK QKELGRLEHV SANELSEFYR DFLNDRHVAM MVYNKEWYRR
     NLQLIWPALK VNVVRFFRMA RR