ID   COA8_CAEEL              Reviewed;         142 AA.
AC   Q8MYM9;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=COA8 family protein Y39B6A.34, mitochondrial {ECO:0000305};
DE            Short=COA8 {ECO:0000305};
DE   AltName: Full=APOPT family protein Y39B6A.34, mitochondrial;
DE   Flags: Precursor;
GN   ORFNames=Y39B6A.34;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: May be required for cytochrome c complex (COX) assembly and
CC       function, COX being the terminal component of the mitochondrial
CC       respiratory chain. {ECO:0000250|UniProtKB:Q96IL0}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9CQW7}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q96IL0}; Matrix side
CC       {ECO:0000250|UniProtKB:Q96IL0}.
CC   -!- SIMILARITY: Belongs to the COA8 family. {ECO:0000305}.
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DR   EMBL; AL132948; CAD31827.1; -; Genomic_DNA.
DR   RefSeq; NP_741663.1; NM_171573.3.
DR   AlphaFoldDB; Q8MYM9; -.
DR   SMR; Q8MYM9; -.
DR   BioGRID; 45207; 5.
DR   DIP; DIP-26157N; -.
DR   STRING; 6239.Y39B6A.34a; -.
DR   EPD; Q8MYM9; -.
DR   PaxDb; Q8MYM9; -.
DR   PeptideAtlas; Q8MYM9; -.
DR   EnsemblMetazoa; Y39B6A.34a.1; Y39B6A.34a.1; WBGene00012693.
DR   GeneID; 180245; -.
DR   KEGG; cel:CELE_Y39B6A.34; -.
DR   UCSC; Y39B6A.34; c. elegans.
DR   CTD; 180245; -.
DR   WormBase; Y39B6A.34a; CE29872; WBGene00012693; -.
DR   eggNOG; KOG4094; Eukaryota.
DR   GeneTree; ENSGT00390000008212; -.
DR   HOGENOM; CLU_118274_0_1_1; -.
DR   InParanoid; Q8MYM9; -.
DR   OMA; TRHNKRF; -.
DR   OrthoDB; 1410150at2759; -.
DR   PhylomeDB; Q8MYM9; -.
DR   PRO; PR:Q8MYM9; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00012693; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   ExpressionAtlas; Q8MYM9; baseline and differential.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:InterPro.
DR   InterPro; IPR018796; COA8.
DR   PANTHER; PTHR31107; PTHR31107; 1.
DR   Pfam; PF10231; DUF2315; 1.
PE   3: Inferred from homology;
KW   Apoptosis; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..142
FT                   /note="COA8 family protein Y39B6A.34, mitochondrial"
FT                   /id="PRO_0000353112"
SQ   SEQUENCE   142 AA;  17459 MW;  00F3BDF0CAD80CD9 CRC64;
     MSSISSSSSN VRMDRRFDWV GPPDNLSKIR KIMLRRVDNE SELERQYRLA REELNQWNSD
     FWAEHNQLFD RQKSDFVERK QQELGRLEHV SANELSEFYR DFLNDRHVAM MAYNKEWYRR
     NLQLIWPALK VNVVRFFRMA RR