2ABA_ORYSJ
ID 2ABA_ORYSJ Reviewed; 581 AA.
AC Q5Z8Z7;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 2.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform;
DE Short=PP2A, subunit B, alpha isoform;
GN OrderedLocusNames=Os06g0563300, LOC_Os06g36770; ORFNames=P0656E03.30;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: The B regulatory subunit may modulate substrate selectivity
CC and catalytic activity, and also may direct the localization of the
CC catalytic enzyme to a particular subcellular compartment.
CC {ECO:0000250}.
CC -!- SUBUNIT: PP2A consists of a common heteromeric enzyme, composed of a
CC catalytic subunit (subunits C), a constant regulatory subunit (subunit
CC A), and a variety of regulatory subunits such as subunits B (the
CC R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit B family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD53757.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP003714; BAD53757.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK111494; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015643857.1; XM_015788371.1.
DR AlphaFoldDB; Q5Z8Z7; -.
DR SMR; Q5Z8Z7; -.
DR STRING; 4530.OS06T0563300-01; -.
DR PaxDb; Q5Z8Z7; -.
DR PRIDE; Q5Z8Z7; -.
DR GeneID; 4341313; -.
DR KEGG; osa:4341313; -.
DR eggNOG; KOG1354; Eukaryota.
DR InParanoid; Q5Z8Z7; -.
DR PlantReactome; R-OSA-5632095; Brassinosteroid signaling.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0000159; C:protein phosphatase type 2A complex; IBA:GO_Central.
DR GO; GO:0019888; F:protein phosphatase regulator activity; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR000009; PP2A_PR55.
DR InterPro; IPR018067; PP2A_PR55_CS.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR11871; PTHR11871; 1.
DR Pfam; PF00400; WD40; 1.
DR PIRSF; PIRSF037309; PP2A_PR55; 1.
DR PRINTS; PR00600; PP2APR55.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS01024; PR55_1; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..581
FT /note="Serine/threonine protein phosphatase 2A 55 kDa
FT regulatory subunit B alpha isoform"
FT /id="PRO_0000247272"
FT REPEAT 47..86
FT /note="WD 1"
FT REPEAT 123..164
FT /note="WD 2"
FT REPEAT 241..279
FT /note="WD 3"
FT REPEAT 290..330
FT /note="WD 4"
FT REPEAT 349..387
FT /note="WD 5"
FT REPEAT 492..530
FT /note="WD 6"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 422
FT /note="H -> Q (in Ref. 3; AK111494)"
FT /evidence="ECO:0000305"
FT CONFLICT 551
FT /note="M -> L (in Ref. 3; AK111494)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 581 AA; 64752 MW; 0E8BB1DA93211BBF CRC64;
MMNPDGGDGD RLEAAGAGSS SAQQGHPTME WRFAQVFGER AAGEDVQEVD IISAIEFDKS
GDHLATGDRG GRVVLFERTD ARDNASRREM ERQDAPITRH PEFRYKSEFQ SHEPEFDYLK
SLEIEEKINK IRWCQTANNS LSLLSTNDKT IKYWKVQEKK VKQVSVMNLD SRSVGTGTSS
SASTSSSRGL LPNGGCSDKS SFLNSDILFP PGGYPSLRLP VVVASQDVNL VARCRRVYAH
AHDYHINSIS TNSDGETYIS ADDLRINLWN LEINNQSFNI VDVKPPNMED LTEVITCAEF
HPTHCNTLAY SSSKGSIRLI DLRQSALCDN HSKIFEEHEA PGSRSFFTEI IASISDIKFS
RDGRYILSRD YMTLKLWDLN MDSGPVSTFQ VHEHLRPKLC DLYENDSIFD KFECCLSGDG
LHVATGSYGN LFRVFGCTPG STEATTLEAS RNPMRRQIVN PTRPTRTLTS LARGVRRGGE
NQGVDANGNS FDFSTKLLHL AWHPTENSIA CAAANSLYMY YARRCLRKFI VFGSLLEAAC
LHMQPEIWCR MLSSIPPLGP KEAVDAHKMA FVAVTASLLI L
