COB22_ORYSJ
ID COB22_ORYSJ Reviewed; 910 AA.
AC Q6H8D5; Q0E2W0;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Coatomer subunit beta'-2;
DE AltName: Full=Beta'-coat protein 2;
DE Short=Beta'-COP 2;
GN OrderedLocusNames=Os02g0209100, LOC_Os02g11840; ORFNames=OJ1006_A02.24;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 290-910.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Golgi apparatus membrane
CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane
CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on
CC the cytoplasmic side of the Golgi, as well as on the vesicles/buds
CC originating from it. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat COPB2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK099955; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AP003977; BAD25014.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF08178.1; -; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK099955; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q6H8D5; -.
DR SMR; Q6H8D5; -.
DR STRING; 39947.Q6H8D5; -.
DR PRIDE; Q6H8D5; -.
DR InParanoid; Q6H8D5; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0030126; C:COPI vesicle coat; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR006692; Coatomer_WD-assoc_reg.
DR InterPro; IPR016453; COPB2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011048; Haem_d1_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF04053; Coatomer_WDAD; 1.
DR Pfam; PF00400; WD40; 4.
DR PIRSF; PIRSF005567; Coatomer_beta'_subunit; 1.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR SUPFAM; SSF51004; SSF51004; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoplasmic vesicle; ER-Golgi transport; Golgi apparatus;
KW Membrane; Protein transport; Reference proteome; Repeat; Transport;
KW WD repeat.
FT CHAIN 1..910
FT /note="Coatomer subunit beta'-2"
FT /id="PRO_0000285608"
FT REPEAT 13..52
FT /note="WD 1"
FT REPEAT 55..94
FT /note="WD 2"
FT REPEAT 97..136
FT /note="WD 3"
FT REPEAT 140..180
FT /note="WD 4"
FT REPEAT 183..224
FT /note="WD 5"
FT REPEAT 227..266
FT /note="WD 6"
FT REPEAT 269..309
FT /note="WD 7"
FT REPEAT 351..393
FT /note="WD 8"
FT REPEAT 461..501
FT /note="WD 9"
FT REGION 882..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 910 AA; 102678 MW; FBA6B1BCE750C481 CRC64;
MPLRLDIKRK LAQRSERVKS VDLHPTEPWI LSSLYSGSVC IWNYQTQTMV KSFEVTELPV
RSSKFIARKQ WIVAGADDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT QPFVLSSSDD
MLIKLWDWDK GWMCTQIFEG HSHYVMQVTF NPKDTNTFAS ASLDRTVKVW SLGSPDPNFT
LDGHSKGVNC VDYFTGGDRP YLITGSDDQT AKVWDYQTKS CVQTLEGHAH NVSAVCFHPE
LPITLTGSED GTVRLWHSTT YRLENTLNYG LERVWALGYM KGSRRVVIGY DEGTIMIKIG
REVPVASMDS SGKIIWSKHN EIQTVNIKTI GADNEIADGE RLPLAVKELG TCDLYPQSLR
HNPNGRFVVV CGDGEYIIYT ALAWRNRSFG SALEFVWSVD GEYAVRESTS RIKIYSKNFQ
ERKSIRPPFS AERIFGGVLL AMCTNDFICF HDWAEGRMIR RIDVNVKNLY WADSGDLVTI
ASDTSFYILK YNRDVVSSHL DGGGSVGEEG VEDAFELLHE INERIRTGLW VGDCFIYNNS
SSRLNYCVGG EVTTLFHLDR QMYLLGYLAN QSRVYLIDKQ FNVVGYTLLL TMIEYKTLVM
RGDFDRANAL LPSIPKEQHD SVARFLESQG MLEEALEIAT DSNYRFDLAV QLGRLEVAKA
IAIEAQSESK WRQLGELAMS TGKLDMAEEC LLHAMDLSGL LLLYSSLGDA EGLTKLTSMA
KEQGKNNVAF LCFFMLGKLE ECLQLLIESN RIPEAALMSR SYLPSKVPEI VTLWKKDLQK
VNPKAAESLA DPDEYPNLFE DWQIALNVEA NVAPKRGIYP PAEEYIIHAE RPNETLVEAF
KSMHIHLEEV LPDENGDDTH EAIEENGVEE SQEDAVEVDV EADGSTDGAV LVNGNDTEEQ
WGTNNEESSA
