ID   COBD_RHOCA              Reviewed;         314 AA.
AC   P0CY56; O68090; Q52683;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Cobalamin biosynthesis protein CobD;
GN   Name=cobD; Synonyms=bluD;
OS   Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=1061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33303 / B10;
RX   PubMed=7635831; DOI=10.1128/jb.177.15.4481-4487.1995;
RA   Pollich M., Klug G.;
RT   "Identification and sequence analysis of genes involved in late steps in
RT   cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus.";
RL   J. Bacteriol. 177:4481-4487(1995).
CC   -!- FUNCTION: Converts cobyric acid to cobinamide by the addition of
CC       aminopropanol on the F carboxylic group. {ECO:0000250}.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CobD/CbiB family. {ECO:0000305}.
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DR   EMBL; Z46611; CAA86581.1; -; Genomic_DNA.
DR   PIR; S52223; S52223.
DR   AlphaFoldDB; P0CY56; -.
DR   UniPathway; UPA00148; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015420; F:ABC-type vitamin B12 transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0048472; F:threonine-phosphate decarboxylase activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00024; CobD_CbiB; 1.
DR   InterPro; IPR004485; Cobalamin_biosynth_CobD/CbiB.
DR   PANTHER; PTHR34308; PTHR34308; 1.
DR   Pfam; PF03186; CobD_Cbib; 1.
DR   TIGRFAMs; TIGR00380; cobD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cobalamin biosynthesis; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Cobalamin biosynthesis protein CobD"
FT                   /id="PRO_0000150935"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   314 AA;  33506 MW;  F4C82DE4AC32E14F CRC64;
     MNFAAMMVVA IGIDLALGWP DALYKRIGHP VTWIARLIAR LEKGWNFKGR LRRLRGVLVA
     LAVIGTTVVI ALAVQLWLPA GWPGVLIGGI LAWPFVALRS MHDHVAAVAK PLIAGDLPGA
     RQAVSMIVGR DPSQLDQPGV ARAALESLAE NSSDGIVAPL FWGCVAGLPG IAGYKAINTL
     DSMIGHRTDR YEEFGWASAR IDDLVNLIPA RLTGLFFALA SPCRARALAV MARDARSHRS
     PNAGWPEAAM AGALAVRLSG PRIYADRVAN EPWLNGTAPD PRPADLARGL ALYRRAMAGM
     TLVIGLVAVL WSVS