COBL1_MOUSE
ID COBL1_MOUSE Reviewed; 1273 AA.
AC Q3UMF0; Q3UX63; Q69ZU2; Q6NXM0; Q7TQM8; Q8BWH3;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Cordon-bleu protein-like 1 {ECO:0000305};
DE AltName: Full=Cobl-related protein 1;
GN Name=Cobll1 {ECO:0000312|MGI:MGI:2442894}; Synonyms=Coblr1, Kiaa0977;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), AND TISSUE SPECIFICITY.
RC TISSUE=Embryo;
RX PubMed=14512015; DOI=10.1016/s0012-1606(03)00323-3;
RA Carroll E.A., Gerrelli D., Gasca S., Berg E., Beier D.R., Copp A.J.,
RA Klingensmith J.;
RT "Cordon-bleu is a conserved gene involved in neural tube formation.";
RL Dev. Biol. 262:16-31(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
RC TISSUE=Pancreatic islet;
RX PubMed=15368895; DOI=10.1093/dnares/11.3.205;
RA Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S.,
RA Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H.,
RA Nagase T., Ohara O., Koga H.;
RT "Prediction of the coding sequences of mouse homologues of KIAA gene: IV.
RT The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs
RT identified by screening of terminal sequences of cDNA clones randomly
RT sampled from size-fractionated libraries.";
RL DNA Res. 11:205-218(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4).
RC STRAIN=C57BL/6J; TISSUE=Egg, Lung, and Mammary gland;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC STRAIN=C57BL/6J; TISSUE=Fetal brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-300; THR-304; SER-373;
RP SER-541; SER-546; SER-551 AND SER-896, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=17242355; DOI=10.1073/pnas.0609836104;
RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
RT "Large-scale phosphorylation analysis of mouse liver.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-546 AND SER-551, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=18630941; DOI=10.1021/pr800223m;
RA Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.;
RT "Specific phosphopeptide enrichment with immobilized titanium ion affinity
RT chromatography adsorbent for phosphoproteome analysis.";
RL J. Proteome Res. 7:3957-3967(2008).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Embryonic fibroblast;
RX PubMed=19131326; DOI=10.1074/mcp.m800451-mcp200;
RA Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.;
RT "Large scale localization of protein phosphorylation by use of electron
RT capture dissociation mass spectrometry.";
RL Mol. Cell. Proteomics 8:904-912(2009).
RN [8]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-183; SER-300; THR-304;
RP THR-328; SER-366; SER-373; SER-374; SER-396; SER-541; SER-546; SER-551;
RP SER-554; SER-645; SER-666; SER-770; SER-896; SER-897; SER-993; SER-1028;
RP SER-1092; SER-1214; SER-1215 AND SER-1266, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
RC Spleen, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=4;
CC Name=1;
CC IsoId=Q3UMF0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3UMF0-2; Sequence=VSP_021626;
CC Name=3;
CC IsoId=Q3UMF0-3; Sequence=VSP_022324, VSP_021627;
CC Name=4;
CC IsoId=Q3UMF0-4; Sequence=VSP_021626, VSP_021627;
CC -!- TISSUE SPECIFICITY: Detected in embryonic first branchial arc,
CC branchial clefts and limb buds. {ECO:0000269|PubMed:14512015}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH67007.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAC35029.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAD32354.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AY308746; AAP74342.1; -; mRNA.
DR EMBL; AK173076; BAD32354.1; ALT_INIT; mRNA.
DR EMBL; AK052533; BAC35029.1; ALT_INIT; mRNA.
DR EMBL; AK135859; BAE22700.1; -; mRNA.
DR EMBL; AK144943; BAE26148.1; -; mRNA.
DR EMBL; BC067007; AAH67007.1; ALT_FRAME; mRNA.
DR CCDS; CCDS50595.1; -. [Q3UMF0-4]
DR CCDS; CCDS89492.1; -. [Q3UMF0-2]
DR RefSeq; NP_081501.1; NM_027225.1. [Q3UMF0-4]
DR RefSeq; NP_795999.2; NM_177025.5.
DR RefSeq; XP_017174487.1; XM_017318998.1.
DR AlphaFoldDB; Q3UMF0; -.
DR SMR; Q3UMF0; -.
DR BioGRID; 235590; 24.
DR IntAct; Q3UMF0; 12.
DR STRING; 10090.ENSMUSP00000099787; -.
DR iPTMnet; Q3UMF0; -.
DR PhosphoSitePlus; Q3UMF0; -.
DR EPD; Q3UMF0; -.
DR jPOST; Q3UMF0; -.
DR MaxQB; Q3UMF0; -.
DR PaxDb; Q3UMF0; -.
DR PeptideAtlas; Q3UMF0; -.
DR PRIDE; Q3UMF0; -.
DR ProteomicsDB; 283333; -. [Q3UMF0-1]
DR ProteomicsDB; 283334; -. [Q3UMF0-2]
DR ProteomicsDB; 283335; -. [Q3UMF0-3]
DR ProteomicsDB; 283336; -. [Q3UMF0-4]
DR Antibodypedia; 33758; 159 antibodies from 18 providers.
DR DNASU; 319876; -.
DR Ensembl; ENSMUST00000090896; ENSMUSP00000088412; ENSMUSG00000034903. [Q3UMF0-4]
DR Ensembl; ENSMUST00000112430; ENSMUSP00000108049; ENSMUSG00000034903. [Q3UMF0-3]
DR GeneID; 319876; -.
DR KEGG; mmu:319876; -.
DR UCSC; uc008jvz.2; mouse. [Q3UMF0-3]
DR UCSC; uc008jwc.2; mouse. [Q3UMF0-4]
DR UCSC; uc008jwe.1; mouse. [Q3UMF0-1]
DR CTD; 22837; -.
DR MGI; MGI:2442894; Cobll1.
DR VEuPathDB; HostDB:ENSMUSG00000034903; -.
DR eggNOG; KOG3751; Eukaryota.
DR GeneTree; ENSGT00530000063608; -.
DR HOGENOM; CLU_003305_0_0_1; -.
DR InParanoid; Q3UMF0; -.
DR OrthoDB; 986623at2759; -.
DR PhylomeDB; Q3UMF0; -.
DR BioGRID-ORCS; 319876; 0 hits in 70 CRISPR screens.
DR ChiTaRS; Cobll1; mouse.
DR PRO; PR:Q3UMF0; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q3UMF0; protein.
DR Bgee; ENSMUSG00000034903; Expressed in interventricular septum and 230 other tissues.
DR ExpressionAtlas; Q3UMF0; baseline and differential.
DR Genevisible; Q3UMF0; MM.
DR GO; GO:0003785; F:actin monomer binding; IEA:InterPro.
DR InterPro; IPR039895; COBL-like.
DR InterPro; IPR019025; Cordon-bleu_ubiquitin_domain.
DR PANTHER; PTHR21557; PTHR21557; 1.
DR Pfam; PF09469; Cobl; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Phosphoprotein; Reference proteome.
FT CHAIN 1..1273
FT /note="Cordon-bleu protein-like 1"
FT /id="PRO_0000260494"
FT DOMAIN 1226..1246
FT /note="WH2"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 958..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1148..1208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1252..1273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 335..340
FT /note="KKRRAP 1"
FT MOTIF 400..405
FT /note="KKRRAP 2"
FT COMPBIAS 310..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..398
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..641
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..782
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..881
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 992..1009
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1069
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 183
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 248
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 266
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 300
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:21183079"
FT MOD_RES 304
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:21183079"
FT MOD_RES 317
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 328
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 366
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 373
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:21183079"
FT MOD_RES 374
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 384
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 396
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 518
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 521
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 541
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:21183079"
FT MOD_RES 546
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:18630941, ECO:0007744|PubMed:21183079"
FT MOD_RES 551
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:18630941, ECO:0007744|PubMed:21183079"
FT MOD_RES 554
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 645
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 666
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 770
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 869
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 896
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17242355,
FT ECO:0007744|PubMed:21183079"
FT MOD_RES 897
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 993
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 999
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53SF7"
FT MOD_RES 1028
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 1092
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 1214
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 1215
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 1266
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT VAR_SEQ 27..59
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_022324"
FT VAR_SEQ 27..58
FT /note="Missing (in isoform 2 and isoform 4)"
FT /evidence="ECO:0000303|PubMed:14512015,
FT ECO:0000303|PubMed:15368895, ECO:0000303|PubMed:16141072"
FT /id="VSP_021626"
FT VAR_SEQ 451..489
FT /note="EGSLGPGFLSQEQCAVPKPPDEISEGPGTPETAVASLTS -> A (in
FT isoform 3 and isoform 4)"
FT /evidence="ECO:0000303|PubMed:15368895,
FT ECO:0000303|PubMed:15489334, ECO:0000303|PubMed:16141072"
FT /id="VSP_021627"
FT CONFLICT 9
FT /note="L -> V (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 211
FT /note="A -> T (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 392
FT /note="I -> V (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 482
FT /note="T -> A (in Ref. 1; AAP74342)"
FT /evidence="ECO:0000305"
FT CONFLICT 557
FT /note="K -> N (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 575
FT /note="G -> C (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 600
FT /note="Missing (in Ref. 1; AAP74342 and 3; BAE22700)"
FT /evidence="ECO:0000305"
FT CONFLICT 654
FT /note="N -> S (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 695
FT /note="G -> D (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 730..731
FT /note="SL -> NV (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 812
FT /note="I -> V (in Ref. 3; BAC35029)"
FT /evidence="ECO:0000305"
FT CONFLICT 828
FT /note="A -> V (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 836
FT /note="M -> V (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 850
FT /note="R -> K (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 908
FT /note="A -> P (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 997
FT /note="H -> R (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1040
FT /note="R -> P (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1049..1050
FT /note="FP -> AA (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1053..1054
FT /note="MT -> VA (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1065
FT /note="F -> A (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1079
FT /note="L -> P (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1176
FT /note="T -> M (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
FT CONFLICT 1184
FT /note="G -> V (in Ref. 3; BAE26148)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1273 AA; 137382 MW; BCC8C8B21D8D87BF CRC64;
MDRSVPDPLP RSAPRTPAMQ PAGSAGKRRF MKMFHAHSKN DFVRIKNHKF LPLHICQSRK
TKGKAPLPPA ETKGTDVSSA EDPVESTAVV TEQQDNMIDK DIELSVVLPG DILKSTTVHG
SKPMMDLLVF LCAQYHLNPS SHTIDLLSAE ENLIKFKPNT PIGMLDVEKV ILKPKSLDKK
KPTPIIPEKT VRVVINFKKT QKTIVRVSPH APLQDLAPII CSKCEFDPLH TVLLKDYQAQ
EPLDLTKSLN DLGLRELYAM DISRESCQIS HNPDIVKEKE NKGIFSFFQR SKKKREQTAS
APATPLVSKH RPSFTRSNTI SKPYISNTLP SDAPKKRRAP LPPMPTSQGA AQGQERRASC
VERSTSVDDT DKSSSEAIMV RTGSLQLSST SIGTSSLKRT KRKAPAPPSK TPLAQTDERN
SAMAHGLPLE DGIAPDSMLE LSSPEGMSTP EGSLGPGFLS QEQCAVPKPP DEISEGPGTP
ETAVASLTSG VSSDYSLEEI DEKEELSEAS KDPAGSISVK SPDIASASTD MRITVEKDPD
SALGISDGET SPSSKGKTQE GRSTEGQGPY HPVVGHIGNE DRVSDSIKDM KTLGPNQESV
VQNEIMVCAT STDYVKNRPG KMETTIEGEG EALKKASDME TDRLSGSPAC RMDNVKSSRE
NHLTASPGPD QKLNQPGVEK TKMQDAAIQA TPARGTFDGN HEVSNSSDPR ADETVQTSDG
SISAQHSSAS LQDSVNASRE FRSQGTSTYV QDRLPEKEPA CTYGNNVPLS PVDGSNKNPA
ASYLKNFPLY RQDSNPKPKP SNEITREYIP KIGMTTYKIV PPKSLEMAKD WESEAMGRKD
DQKMLPVGQR HTIENMTETS MQTEVPATSK SSQQPQPDLK PKPSSGTERH LHRTLSSPTG
TETNPPKAPR VTTDTGTIPF APNLEDINNI LESKFRSRAS NPQAKPSSFF LQMQKRASGH
YVTSAAAKSV HTAPGPAPKE PTIKEVQRDP QLSPEQHPSS LSERTHSAPL PNISKADDDI
IQKPAETSPP PVAPKPMTLR AETSPPPVFP KPMTLPAETS PPPVFPKPMT LPAETSLPLV
FPKPMTLRAE TSPPPVAAKP VALPGSQGTS LNLKTLKTFG APRPYSSSGP SPFALAVVKR
SQSFSKACPE SASEGSSALP PAATQDEKTH TVNKPTVGSQ HGDGDKQNNP VQNEHSSQVL
TPADGPSFTL KRQSSLTFQS SDPEHVRQSL LTAIRSGEAA AKLKRVTVPS NTISVNGKSG
LSQSMSIDAQ DSR
