COBL2_ARATH
ID COBL2_ARATH Reviewed; 441 AA.
AC Q8L8Q7; Q9FWK1; Q9LJ49;
DT 22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2003, sequence version 2.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=COBRA-like protein 2;
DE Flags: Precursor;
GN Name=COBL2; OrderedLocusNames=At3g29810; ORFNames=K17E7.7;
GN and
GN Name=COBL3; OrderedLocusNames=At1gXXXXX; ORFNames=F21N10.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=12376623; DOI=10.1104/pp.007468;
RA Roudier F., Schindelman G., DeSalle R., Benfey P.N.;
RT "The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new
RT fellowship in expansion.";
RL Plant Physiol. 130:538-548(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and
CC siliques. {ECO:0000269|PubMed:12376623}.
CC -!- SIMILARITY: Belongs to the COBRA family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG12670.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAB02996.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP000736; BAB02996.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC027033; AAG12670.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77616.1; -; Genomic_DNA.
DR EMBL; AY088873; AAM67179.1; -; mRNA.
DR RefSeq; NP_566851.1; NM_113910.5.
DR AlphaFoldDB; Q8L8Q7; -.
DR STRING; 3702.AT3G29810.1; -.
DR PaxDb; Q8L8Q7; -.
DR PRIDE; Q8L8Q7; -.
DR ProteomicsDB; 241054; -.
DR EnsemblPlants; AT3G29810.1; AT3G29810.1; AT3G29810.
DR GeneID; 822697; -.
DR Gramene; AT3G29810.1; AT3G29810.1; AT3G29810.
DR KEGG; ath:AT3G29810; -.
DR Araport; AT3G29810; -.
DR TAIR; locus:2086601; AT3G29810.
DR eggNOG; ENOG502QTGW; Eukaryota.
DR HOGENOM; CLU_038120_0_0_1; -.
DR OMA; INSWAQE; -.
DR OrthoDB; 494933at2759; -.
DR PhylomeDB; Q8L8Q7; -.
DR PRO; PR:Q8L8Q7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8L8Q7; baseline and differential.
DR Genevisible; Q8L8Q7; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0046658; C:anchored component of plasma membrane; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0005797; C:Golgi medial cisterna; HDA:TAIR.
DR GO; GO:0010215; P:cellulose microfibril organization; IMP:TAIR.
DR GO; GO:0048354; P:mucilage biosynthetic process involved in seed coat development; IMP:TAIR.
DR GO; GO:0009832; P:plant-type cell wall biogenesis; IMP:TAIR.
DR GO; GO:0052324; P:plant-type cell wall cellulose biosynthetic process; IMP:TAIR.
DR GO; GO:0009664; P:plant-type cell wall organization; IMP:TAIR.
DR GO; GO:0010214; P:seed coat development; IMP:TAIR.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR InterPro; IPR006918; COBRA_pln.
DR PANTHER; PTHR31673; PTHR31673; 1.
DR Pfam; PF04833; COBRA; 1.
DR PIRSF; PIRSF038122; COBRA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Reference proteome; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..417
FT /note="COBRA-like protein 2"
FT /id="PRO_0000005574"
FT PROPEP 418..441
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000005575"
FT LIPID 417
FT /note="GPI-anchor amidated asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 37
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 162
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 170
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 209
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 234
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 249
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 314
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 329
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 348
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 20
FT /note="S -> I (in Ref. 4; AAM67179)"
FT /evidence="ECO:0000305"
FT CONFLICT 322
FT /note="V -> F (in Ref. 4; AAM67179)"
FT /evidence="ECO:0000305"
FT CONFLICT 332
FT /note="K -> Q (in Ref. 4; AAM67179)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 441 AA; 49697 MW; D996E89ECE02BEEE CRC64;
MNILFSRFSF LLLFLCSWTS FTFTTTEAYD ALDPYGNITI KWDIMSWTGD GYVAVVTIFN
FQQYRHIEAP GWQLGWSWMK KEVIWSMVGG QATEQGDCSK FKGNIPHCCK KTPAIVDLLP
GTPYNQQISN CCRGGVISAW AQDPATAISS FQISVGQSGT TNTTVRAPRN ITLKAPGPGY
TCGPAKLVKP SRFISADKRR KTQSLLTWNI TCTYSQFLAR KTPTCCVSLS AFYNETIVPC
PTCSCGCQNS SQAGTCVDPK IASVVPALGK NNLEPLLQCT QHMCPIRVHW HVKTSYKEYW
RVKVAITNFN YNMNYSQWNL VVQHPNFDNL TKLFSFNYKP LNPYLNINDT AMLWGIKFYN
DFLSQAGPVG NVQSELLFQK NPLEFTFEKG WAFPRRIYFN GDNCVMPPPD SYPWLPNASP
NIATSPFVIL LITFLSVLIL M
