COBL4_ARATH
ID COBL4_ARATH Reviewed; 431 AA.
AC Q9LFW3; Q6ICX3;
DT 22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2003, sequence version 2.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=COBRA-like protein 4;
DE Flags: Precursor;
GN Name=COBL4; OrderedLocusNames=At5g15630; ORFNames=F14F8_10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=12376623; DOI=10.1104/pp.007468;
RA Roudier F., Schindelman G., DeSalle R., Benfey P.N.;
RT "The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new
RT fellowship in expansion.";
RL Plant Physiol. 130:538-548(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and
CC siliques. {ECO:0000269|PubMed:12376623}.
CC -!- SIMILARITY: Belongs to the COBRA family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC01762.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL391144; CAC01762.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92186.1; -; Genomic_DNA.
DR EMBL; BT014900; AAT44976.1; -; mRNA.
DR EMBL; BT020445; AAW30024.1; -; mRNA.
DR PIR; T51392; T51392.
DR RefSeq; NP_001331538.1; NM_001343412.1.
DR RefSeq; NP_197067.2; NM_121567.5.
DR AlphaFoldDB; Q9LFW3; -.
DR STRING; 3702.AT5G15630.1; -.
DR PaxDb; Q9LFW3; -.
DR PRIDE; Q9LFW3; -.
DR EnsemblPlants; AT5G15630.1; AT5G15630.1; AT5G15630.
DR GeneID; 831417; -.
DR Gramene; AT5G15630.1; AT5G15630.1; AT5G15630.
DR KEGG; ath:AT5G15630; -.
DR Araport; AT5G15630; -.
DR TAIR; locus:2143151; AT5G15630.
DR eggNOG; ENOG502QQYT; Eukaryota.
DR HOGENOM; CLU_038120_0_0_1; -.
DR InParanoid; Q9LFW3; -.
DR OMA; CACGCDA; -.
DR OrthoDB; 623715at2759; -.
DR PhylomeDB; Q9LFW3; -.
DR PRO; PR:Q9LFW3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LFW3; baseline and differential.
DR Genevisible; Q9LFW3; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0046658; C:anchored component of plasma membrane; IBA:GO_Central.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0010215; P:cellulose microfibril organization; IEA:InterPro.
DR GO; GO:0052324; P:plant-type cell wall cellulose biosynthetic process; IBA:GO_Central.
DR GO; GO:0009834; P:plant-type secondary cell wall biogenesis; IMP:TAIR.
DR InterPro; IPR006918; COBRA_pln.
DR PANTHER; PTHR31673; PTHR31673; 1.
DR Pfam; PF04833; COBRA; 1.
DR PIRSF; PIRSF038122; COBRA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Reference proteome; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..414
FT /note="COBRA-like protein 4"
FT /id="PRO_0000005576"
FT PROPEP 415..431
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000005577"
FT LIPID 414
FT /note="GPI-anchor amidated asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 29
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 154
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 162
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 201
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 226
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 306
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 321
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 340
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 431 AA; 48515 MW; B75A23BAA2848A21 CRC64;
MRLLFSFCFF FFMIIFTATA YDPLDPSGNI TIKWDIMSWT ADGYVATVTM NNFQIYRHIQ
NPGWTLGWTW AKKEVIWSMV GAQTTEQGDC SKFKGNVPHC CKKTPTVVDL LPGVPYNQQF
SNCCKGGVIG AWGQDPSAAV SQFQVSAGLA GTTNKTVKLP KNFTLLGPGP GYTCGPAKIV
PSTVFLTTDK RRKTQALMTW NVTCTYSQFL ARKHPSCCVS FSSFYNDTIT PCPSCACGCE
NKKSCVKADS KILTKKGLNT PKKDNTPLLQ CTHHMCPVRV HWHVKTNYKD YWRVKIAITN
FNYRMNHTLW TLAIQHPNLN NVTQVFSFDY KPVSPYGSIN DTGMFYGTKF YNDLLMEAGP
SGNVQSEVLL QKDQKTFTFK QGWAFPRKVY FNGDECMLPP PDSYPFLPNS AQGNFASFSL
TILLLLFISI W
