COCH_PEA
ID COCH_PEA Reviewed; 483 AA.
AC G8GTN7; G8GTN8;
DT 05-DEC-2018, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 1.
DT 03-AUG-2022, entry version 36.
DE RecName: Full=BTB/POZ domain and ankyrin repeat-containing protein COCH {ECO:0000305};
DE AltName: Full=Protein COCHLEATA {ECO:0000303|PubMed:10948249};
GN Name=COCH {ECO:0000303|PubMed:10948249};
OS Pisum sativum (Garden pea).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX NCBI_TaxID=3888;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=23136374; DOI=10.1105/tpc.112.103747;
RA Couzigou J.M., Zhukov V., Mondy S., Abu El Heba G., Cosson V., Ellis T.H.,
RA Ambrose M., Wen J., Tadege M., Tikhonovich I., Mysore K.S., Putterill J.,
RA Hofer J., Borisov A.Y., Ratet P.;
RT "NODULE ROOT and COCHLEATA maintain nodule development and are legume
RT orthologs of Arabidopsis BLADE-ON-PETIOLE genes.";
RL Plant Cell 24:4498-4510(2012).
RN [2]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=10948249; DOI=10.2307/3871129;
RA Gourlay C.W., Hofer J.M., Ellis T.H.;
RT "Pea compound leaf architecture is regulated by interactions among the
RT genes UNIFOLIATA, cochleata, afila, and tendril-lessn.";
RL Plant Cell 12:1279-1294(2000).
RN [3]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=16043431; DOI=10.1093/pcp/pci171;
RA Ferguson B.J., Reid J.B.;
RT "Cochleata: getting to the root of legume nodules.";
RL Plant Cell Physiol. 46:1583-1589(2005).
RN [4]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=19488780; DOI=10.1007/s00425-009-0952-0;
RA Kumar S., Mishra R.K., Kumar A., Srivastava S., Chaudhary S.;
RT "Regulation of stipule development by COCHLEATA and STIPULE-REDUCED genes
RT in pea Pisum sativum.";
RL Planta 230:449-458(2009).
RN [5]
RP FUNCTION.
RX PubMed=23151794; DOI=10.1007/s12038-012-9263-x;
RA Sharma V., Chaudhary S., Kumar A., Kumar S.;
RT "COCHLEATA controls leaf size and secondary inflorescence architecture via
RT negative regulation of UNIFOLIATA (LEAFY ortholog) gene in garden pea Pisum
RT sativum.";
RL J. Biosci. 37:1041-1059(2012).
CC -!- FUNCTION: Involved in the promotion of leaf and floral meristem fate
CC and determinacy (PubMed:23136374, PubMed:23151794). Promotes normal
CC stipule growth and development (PubMed:23136374, PubMed:10948249,
CC PubMed:19488780). Down-regulates UNI expression in primordia of leaves
CC and secondary inflorescences, and thereby controls their sizes and/or
CC structures (PubMed:23151794). Involved in the coordination of the
CC symbiotic nodule developmental program (PubMed:16043431). Necessary for
CC the robust maintenance of nodule identity throughout the nodule
CC developmental program (PubMed:16043431). {ECO:0000269|PubMed:10948249,
CC ECO:0000269|PubMed:16043431, ECO:0000269|PubMed:19488780,
CC ECO:0000269|PubMed:23136374, ECO:0000269|PubMed:23151794}.
CC -!- DISRUPTION PHENOTYPE: Altered morphology of stipules (PubMed:23136374,
CC PubMed:10948249, PubMed:19488780). Altered morphology of flowers
CC (PubMed:23136374). Production of abnormal nodules that develop roots
CC from the apical part of the nodule (PubMed:16043431).
CC {ECO:0000269|PubMed:10948249, ECO:0000269|PubMed:16043431,
CC ECO:0000269|PubMed:19488780, ECO:0000269|PubMed:23136374}.
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DR EMBL; JN180860; AET34790.1; -; Genomic_DNA.
DR EMBL; JN180861; AET34791.1; -; mRNA.
DR EMBL; JN180862; AET34792.1; -; Genomic_DNA.
DR AlphaFoldDB; G8GTN7; -.
DR SMR; G8GTN7; -.
DR EnsemblPlants; Psat3g077680.2; Psat3g077680.2.cds; Psat3g077680.
DR Gramene; Psat3g077680.2; Psat3g077680.2.cds; Psat3g077680.
DR GO; GO:0009908; P:flower development; IMP:UniProtKB.
DR GO; GO:0048366; P:leaf development; IMP:UniProtKB.
DR GO; GO:0009877; P:nodulation; IEA:UniProtKB-KW.
DR GO; GO:0010865; P:stipule development; IMP:UniProtKB.
DR Gene3D; 1.25.40.20; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR044284; NPR5/6.
DR InterPro; IPR024228; NPR_central_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46668; PTHR46668; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF11900; DUF3420; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF48403; SSF48403; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW ANK repeat; Nodulation; Repeat.
FT CHAIN 1..483
FT /note="BTB/POZ domain and ankyrin repeat-containing protein
FT COCH"
FT /id="PRO_0000445729"
FT DOMAIN 25..105
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT REPEAT 249..278
FT /note="ANK 1"
FT /evidence="ECO:0000255"
FT REPEAT 279..308
FT /note="ANK 2"
FT /evidence="ECO:0000255"
FT REPEAT 313..342
FT /note="ANK 3"
FT /evidence="ECO:0000255"
FT REGION 395..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..483
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 387
FT /note="S -> F (in Ref. 1; AET34792)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 483 AA; 53573 MW; 56D123D13026A4B8 CRC64;
MSLEDSLRSL SLDYLNLLIN GQAFSDVVFS VEGRLVHAHR CILAARSLFF RKFFCGPDPP
SGLDPSGNRV NSSTRSGVIP VNSVGYEVFL LMLQFLYSGQ VSIVPQKHEP RPNCGDRGCW
HTHCTSAVDL ALDTLSAARY FGVEQLALLT QKQLASMVEK ASIEDVMKVL LASRKQDMHQ
LWTTCSHLVA KSGLPPEVLA KHLPIDIIAK IEELRMKSSL SRRSLIPHHH HNPHHHHDHL
TAAADLEDQK IRRMRRALDS SDVELVKLMV MGEGLNLDEA LALPYAVESC SREVVKALLE
LGAADVNFPA GPTGKTPLHI AAEMVSPDMV AVLLDHHADP NVRTVDGVTP LDILRTLTSD
FLFKGAVPGL THIEPNKLRL CLELVQSAAL VMSREEGNNN NNANNNNTGS SATNMYPHNH
MNEEHHSHHN NNSNMDSRLV YLNLGANTQM STSRLDSGDD DHNSNQREAM NPSMYHHHHS
HDY
