ACP2_ARATH
ID ACP2_ARATH Reviewed; 136 AA.
AC P25701; Q9ZVN1;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 157.
DE RecName: Full=Acyl carrier protein 2, chloroplastic;
DE Short=ACP-2;
DE Flags: Precursor;
GN Name=ACP2; Synonyms=A1, ACL1.2; OrderedLocusNames=At1g54580;
GN ORFNames=T22H22.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=1893112; DOI=10.1007/bf00023997;
RA Lamppa G., Jacks C.;
RT "Analysis of two linked genes coding for the acyl carrier protein (ACP)
RT from Arabidopsis thaliana (columbia).";
RL Plant Mol. Biol. 16:469-474(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP CHARACTERIZATION.
RX PubMed=16668615; DOI=10.1104/pp.98.1.206;
RA Hlousek-Radojcic A., Post-Beittenmiller D., Ohlrogge J.B.;
RT "Expression of constitutive and tissue-specific acyl carrier protein
RT isoforms in Arabidopsis.";
RL Plant Physiol. 98:206-214(1992).
RN [6]
RP INDUCTION.
RX PubMed=11788768; DOI=10.1104/pp.010397;
RA Bonaventure G., Ohlrogge J.B.;
RT "Differential regulation of mRNA levels of acyl carrier protein isoforms in
RT Arabidopsis.";
RL Plant Physiol. 128:223-235(2002).
CC -!- FUNCTION: Carrier of the growing fatty acid chain in fatty acid
CC biosynthesis.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC -!- INDUCTION: By sucrose in the dark. Down-regulated by starvation.
CC {ECO:0000269|PubMed:11788768}.
CC -!- PTM: 4'-phosphopantetheine is transferred from CoA to a specific serine
CC of apo-ACP by acpS. This modification is essential for activity because
CC fatty acids are bound in thioester linkage to the sulfhydryl of the
CC prosthetic group (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the acyl carrier protein (ACP) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB63798.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; X57698; CAB63798.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC005388; AAC64875.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33121.1; -; Genomic_DNA.
DR EMBL; AY062773; AAL32851.1; -; mRNA.
DR EMBL; AY081661; AAM10223.1; -; mRNA.
DR PIR; H96587; H96587.
DR PIR; S14964; S14964.
DR RefSeq; NP_175860.1; NM_104336.5.
DR AlphaFoldDB; P25701; -.
DR SMR; P25701; -.
DR BioGRID; 27125; 1.
DR STRING; 3702.AT1G54580.1; -.
DR iPTMnet; P25701; -.
DR PaxDb; P25701; -.
DR PRIDE; P25701; -.
DR ProteomicsDB; 244394; -.
DR EnsemblPlants; AT1G54580.1; AT1G54580.1; AT1G54580.
DR GeneID; 841900; -.
DR Gramene; AT1G54580.1; AT1G54580.1; AT1G54580.
DR KEGG; ath:AT1G54580; -.
DR Araport; AT1G54580; -.
DR TAIR; locus:2199461; AT1G54580.
DR eggNOG; KOG1748; Eukaryota.
DR HOGENOM; CLU_108696_1_0_1; -.
DR InParanoid; P25701; -.
DR OMA; MSFMSIR; -.
DR OrthoDB; 1473625at2759; -.
DR PhylomeDB; P25701; -.
DR PRO; PR:P25701; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P25701; baseline and differential.
DR Genevisible; P25701; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0000036; F:acyl carrier activity; IDA:TAIR.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0019904; F:protein domain specific binding; IPI:CAFA.
DR Gene3D; 1.10.1200.10; -; 1.
DR HAMAP; MF_01217; Acyl_carrier; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR044813; ACP_chloroplastic.
DR InterPro; IPR003231; Acyl_carrier.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR46153; PTHR46153; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; SSF47336; 1.
DR TIGRFAMs; TIGR00517; acyl_carrier; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Fatty acid biosynthesis; Fatty acid metabolism;
KW Lipid biosynthesis; Lipid metabolism; Phosphopantetheine; Phosphoprotein;
KW Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..51
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 52..136
FT /note="Acyl carrier protein 2, chloroplastic"
FT /id="PRO_0000000569"
FT DOMAIN 56..131
FT /note="Carrier"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
FT MOD_RES 91
FT /note="O-(pantetheine 4'-phosphoryl)serine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
SQ SEQUENCE 136 AA; 14528 MW; 6F4E5B2A773F8375 CRC64;
MASIAASASI SLQARPRQLA IAASQVKSFS NGRRSSLSFN LRQLPTRLTV SCAAKPETVD
KVCAVVRKQL SLKEADEITA ATKFAALGAD SLDTVEIVMG LEEEFGIEMA EEKAQSIATV
EQAAALIEEL LFEKAK
