ID   COG2_SCHPO              Reviewed;         191 AA.
AC   O59705;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 2;
DE            Short=COG complex subunit 2;
DE   AltName: Full=Component of oligomeric Golgi complex 2;
GN   Name=cog2; ORFNames=SPBC36.08c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for normal Golgi morphology and function.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC       composed of eight different subunits and is required for normal Golgi
CC       morphology and localization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000269|PubMed:16823372}; Peripheral membrane protein
CC       {ECO:0000269|PubMed:16823372}; Cytoplasmic side
CC       {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the COG2 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA19056.2; -; Genomic_DNA.
DR   PIR; T40303; T40303.
DR   RefSeq; NP_595336.1; NM_001021244.2.
DR   AlphaFoldDB; O59705; -.
DR   SMR; O59705; -.
DR   BioGRID; 276906; 2.
DR   STRING; 4896.SPBC36.08c.1; -.
DR   iPTMnet; O59705; -.
DR   MaxQB; O59705; -.
DR   PaxDb; O59705; -.
DR   PRIDE; O59705; -.
DR   EnsemblFungi; SPBC36.08c.1; SPBC36.08c.1:pep; SPBC36.08c.
DR   GeneID; 2540377; -.
DR   KEGG; spo:SPBC36.08c; -.
DR   PomBase; SPBC36.08c; cog2.
DR   VEuPathDB; FungiDB:SPBC36.08c; -.
DR   HOGENOM; CLU_1428770_0_0_1; -.
DR   InParanoid; O59705; -.
DR   OMA; EDEFTPD; -.
DR   PhylomeDB; O59705; -.
DR   PRO; PR:O59705; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISO:PomBase.
DR   GO; GO:0007030; P:Golgi organization; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:PomBase.
DR   GO; GO:0000301; P:retrograde transport, vesicle recycling within Golgi; ISO:PomBase.
DR   InterPro; IPR009316; COG2.
DR   InterPro; IPR024602; COG_su2_N.
DR   PANTHER; PTHR12961; PTHR12961; 1.
DR   Pfam; PF06148; COG2; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Nucleus; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..191
FT                   /note="Conserved oligomeric Golgi complex subunit 2"
FT                   /id="PRO_0000339334"
SQ   SEQUENCE   191 AA;  21829 MW;  D7461ACE5A28A19A CRC64;
     MTEKDADSGS DLVDAFLSDA YLNTEELRKD GPFSPDEFLV SKRFLGLDGL VNELSRLFEQ
     VNNELMLLVK DNYQDFVHLG SRMKSGNTKV STLISSIHRS EEQLKNSKQS LIGHSTEIQN
     NLKHKQDVEN EKLIASNLLL LDQILKFLKS NDSSHPLWLE SLNNAQRLCD TYKDHPWVQS
     ISPTLINYIK H