ID   COG4_DICDI              Reviewed;         911 AA.
AC   Q55FT5;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 4;
DE            Short=COG complex subunit 4;
DE   AltName: Full=Component of oligomeric Golgi complex 4;
GN   Name=cog4; ORFNames=DDB_G0267960;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for normal Golgi function.
CC       {ECO:0000250|UniProtKB:Q9H9E3}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC       composed of eight different subunits and is required for normal Golgi
CC       morphology and localization. {ECO:0000250|UniProtKB:Q9H9E3}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q9H9E3}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q9H9E3}.
CC   -!- SIMILARITY: Belongs to the COG4 family. {ECO:0000305}.
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DR   EMBL; AAFI02000003; EAL73433.1; -; Genomic_DNA.
DR   RefSeq; XP_647448.1; XM_642356.1.
DR   AlphaFoldDB; Q55FT5; -.
DR   SMR; Q55FT5; -.
DR   STRING; 44689.DDB0237854; -.
DR   PaxDb; Q55FT5; -.
DR   EnsemblProtists; EAL73433; EAL73433; DDB_G0267960.
DR   GeneID; 8616255; -.
DR   KEGG; ddi:DDB_G0267960; -.
DR   dictyBase; DDB_G0267960; cog4.
DR   eggNOG; KOG0412; Eukaryota.
DR   HOGENOM; CLU_014853_2_0_1; -.
DR   InParanoid; Q55FT5; -.
DR   OMA; SECQQRV; -.
DR   PhylomeDB; Q55FT5; -.
DR   PRO; PR:Q55FT5; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR013167; COG_su4.
DR   Pfam; PF08318; COG4; 1.
DR   SMART; SM00762; Cog4; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..911
FT                   /note="Conserved oligomeric Golgi complex subunit 4"
FT                   /id="PRO_0000339134"
FT   REGION          496..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   911 AA;  106365 MW;  AD8A7A7B0C0BC19D CRC64;
     MDELIVDFNN LDSNLSIDDA KKYLQNLISR DKAIEINLKQ HIKLKDDLEI QMESFDNEIP
     EYLTLSLKKS NELNNRISST CQLAENLSSK VKKLDNIRER IKDTLKKVDD IIDLKNCIEG
     VQISIEKEDY EGAAFHINRY LSIDKSVLED NSSEKLSIAE KKLLSMIESK YQQSLQDNDQ
     KQVLRFCILY VPLEKPLEGI DKYCNYLKNQ SKKLDAMITH YRNYIQSPKT IKPISAVSVI
     TKIFEHFAAI IEDDLPIIKS EFGVLHCPHF ILNITQQCDY YSSKVYDSFN DQFQTNKNVN
     DILVYKQQLE KSQQSIQDSG SGSGGGGGKV SEKIDPRNFA QFLDETSMIS KATKFYEKYL
     IRKEHLIKSD IYQYYSKLEK EKIEKLNSIK SLIITNSRNQ QLQQLPQPQQ LQQQQQYQQQ
     LQTQENKENE LLKKLTQEKD KQMKQTIYSN VTKQKMNQLL GNYILLEEYF MVESVNKAIQ
     MDSLQSLDFE NNINSSNSNS SSVSGSGIGG SNTLSSSNSQ QSQQSTDNTM IDFIFFVLQK
     SLQRAIDSHS IQTLNVICNR LCRILSQTRD NLKRIFREYI IRSSSKSVMD YQSSLQVLNN
     LETSSEYIIR LKKEFDSKCL KIYPIYKLDE KSKDLESSST SSTSIEQQQQ QQQQQQQQQQ
     QQQQQQQQQQ QQQEQQQENE FESNLKDDII IIRNLLNLEL KKKQENDRDQ VNILSNEFLN
     CSKSFNKILQ EEIESLFKSV QPRLKNVLNQ FTLVNYEINQ LEYDNNDIND PFVLQFTLEI
     SHFFKPFQEH LSNTNYDYLV HQTIQFILKK IEGITIQQKK FTLLGGLQFG KDLRAISTYF
     TKISQSTIRD KFSKLNQISS FLILESISEV EDHWNENRNS PTWKLSSSEV QKILMTRIDF
     NHDQILKLKF N