COG5_BOVIN
ID COG5_BOVIN Reviewed; 31 AA.
AC P83437;
DT 30-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2002, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 5;
DE Short=COG complex subunit 5;
DE AltName: Full=13S Golgi transport complex 90 kDa subunit;
DE Short=GTC-90;
DE AltName: Full=Component of oligomeric Golgi complex 5;
DE Flags: Fragments;
GN Name=COG5;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Brain;
RX PubMed=9792665; DOI=10.1074/jbc.273.45.29565;
RA Walter D.M., Paul K.S., Waters M.G.;
RT "Purification and characterization of a novel 13 S hetero-oligomeric
RT protein complex that stimulates in vitro Golgi transport.";
RL J. Biol. Chem. 273:29565-29576(1998).
RN [2]
RP SUBUNIT.
RX PubMed=11980916; DOI=10.1083/jcb.200202016;
RA Ungar D., Oka T., Brittle E.E., Vasile E., Lupashin V.V., Chatterton J.E.,
RA Heuser J.E., Krieger M., Waters M.G.;
RT "Characterization of a mammalian Golgi-localized protein complex, COG, that
RT is required for normal Golgi morphology and function.";
RL J. Cell Biol. 157:405-415(2002).
CC -!- FUNCTION: Required for normal Golgi function. {ECO:0000250}.
CC -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC composed of eight different subunits and is required for normal Golgi
CC morphology and localization. {ECO:0000269|PubMed:11980916}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus
CC membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COG5 family. {ECO:0000305}.
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DR AlphaFoldDB; P83437; -.
DR OrthoDB; 871605at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cytoplasm; Direct protein sequencing; Golgi apparatus; Membrane;
KW Protein transport; Reference proteome; Transport.
FT CHAIN <1..>31
FT /note="Conserved oligomeric Golgi complex subunit 5"
FT /id="PRO_0000213509"
FT NON_CONS 10..11
FT /evidence="ECO:0000305"
FT NON_CONS 21..22
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 31
SQ SEQUENCE 31 AA; 3311 MW; 1E694B8E657AAD45 CRC64;
IGALQGAVDR VLTQPTQSIV RNVAVVNSLY K