ID   COG5_SCHPO              Reviewed;         411 AA.
AC   O42962;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 5;
DE            Short=COG complex subunit 5;
GN   Name=cog5; ORFNames=SPBC19G7.14c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Acts as essential component of the peripheral membrane COG
CC       complex that is involved in intra-Golgi protein trafficking. COG is
CC       located at the cis-Golgi, and regulates tethering of retrograde intra-
CC       Golgi vesicles and possibly a number of other membrane trafficking
CC       events (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi (COG) complex
CC       which consists of eight different proteins cog1-cog8. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi
CC       apparatus membrane {ECO:0000269|PubMed:16823372}; Peripheral membrane
CC       protein {ECO:0000269|PubMed:16823372}; Cytoplasmic side
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the COG5 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329671; CAA17068.1; -; Genomic_DNA.
DR   PIR; T39845; T39845.
DR   RefSeq; NP_595980.1; NM_001021887.2.
DR   AlphaFoldDB; O42962; -.
DR   STRING; 4896.SPBC19G7.14c.1; -.
DR   MaxQB; O42962; -.
DR   PaxDb; O42962; -.
DR   PRIDE; O42962; -.
DR   EnsemblFungi; SPBC19G7.14c.1; SPBC19G7.14c.1:pep; SPBC19G7.14c.
DR   GeneID; 2540782; -.
DR   KEGG; spo:SPBC19G7.14c; -.
DR   PomBase; SPBC19G7.14c; cog5.
DR   VEuPathDB; FungiDB:SPBC19G7.14c; -.
DR   HOGENOM; CLU_669316_0_0_1; -.
DR   InParanoid; O42962; -.
DR   OMA; IWSKFED; -.
DR   PRO; PR:O42962; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; ISO:PomBase.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; ISO:PomBase.
DR   GO; GO:0006886; P:intracellular protein transport; IC:PomBase.
DR   InterPro; IPR019465; Cog5.
DR   PANTHER; PTHR13228; PTHR13228; 1.
DR   Pfam; PF10392; COG5; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Golgi apparatus; Membrane; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..411
FT                   /note="Conserved oligomeric Golgi complex subunit 5"
FT                   /id="PRO_0000116762"
SQ   SEQUENCE   411 AA;  47518 MW;  143E36915D1D15BD CRC64;
     MEFRYDFSDY KKSDFDPKAQ AERVLISVHA DSDVNEDKEV ARKRLGYALK EVERQITDLI
     VHEETTLTKN VSSSLNAQSY LQDIEGKLEQ LMLVYERIRS LVVIPSENLG PLHEAIVNLH
     STYMTLYWLG EFFGIQAKLF PLFQGSINEN EKLSRYYQAS LLLQESDQLL SRFPLMKRQS
     SVSLLLKLNI TNRSRIIKET SSYLLSQEDQ LSFSVNSNGF TNACSVLYML DKYLLEQDLT
     RLLSSRIQKA IIQFDSIFQL SPTTRRLLHN STDPSAANST IWSKFEDGWY QISKIGAQCV
     FWERSLQKAN ICNPDYPNLL EYFQMQPNFI LDGATICIYF FKELAISISS KMQMLDRRDP
     ILLRVFRSDF QRVTHIVEQA IARSSSEIVN KDTRECSIVM NSLRVLAPKN P