ID   COG6_ASPFU              Reviewed;         752 AA.
AC   Q4WLS7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=cog6; ORFNames=AFUA_6G12470;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR   EMBL; AAHF01000006; EAL89087.1; -; Genomic_DNA.
DR   RefSeq; XP_751125.1; XM_746032.1.
DR   AlphaFoldDB; Q4WLS7; -.
DR   STRING; 746128.CADAFUBP00007649; -.
DR   EnsemblFungi; EAL89087; EAL89087; AFUA_6G12470.
DR   GeneID; 3508432; -.
DR   KEGG; afm:AFUA_6G12470; -.
DR   VEuPathDB; FungiDB:Afu6g12470; -.
DR   eggNOG; KOG3758; Eukaryota.
DR   HOGENOM; CLU_011361_1_0_1; -.
DR   InParanoid; Q4WLS7; -.
DR   OMA; RFYQQIM; -.
DR   OrthoDB; 1370285at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..752
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339313"
FT   REGION          600..620
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          709..736
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   752 AA;  83324 MW;  163C9DDF449ED164 CRC64;
     MESYFPSGAI ANHSFIRASS PASTPLSPPT QRSNALSNRL TSVLSASYAD SDIRDALETL
     SLRGVHNTAE TRRQLRLDVQ KEVVECNAEI VRDFGKVAEQ LQRIGTVISS LNQTCEEMRQ
     HIVRAKQDTA PVIEEASALM NQKKESETKQ QLLDAFVKHF IVSEDDLLVL TSAEEPIDDR
     FFNVLDRVKQ VHHDCEVLLG GENQRLGLEL MEKSSRNLNS AYQKLFRWIQ KKFKSLNLED
     PRISSSIRRA LRVLAERPSL FHSCLDFFAD ARDYALSDAF HYALTDTVSG SGGDRNVKPI
     EFSAHDPLRY VGDMLAWVHS TTVSEREALE ALFVADGEEI AKGIQAGLSS EPWSRIDEGE
     EVSFDGRKAL NDLVNRDLVG VSRALRQRIE LVIQGHDEPV TCYKVVHLLS FYRATFSRLL
     GTKSNLADMM QTLEKFTFSR FESLMLEQVN TLSNDHAALT PPDDLSAPEF FLDALEELTS
     LMKTHDASLE AEDAESESTA ENKFTPVLRV AFDPFLQLAK SSAAELPDAT ARAIYTTNVL
     LTARSTISAF AFASATHMDP ISTALSSLRM ELLEIQHRYL LDASGLGVLL TALEPFAPSP
     TISKPESEGK DGHAPPQVDK QPTDIAEIAD LPAFQPEALI AVGQQLDDFL PSALMDATDN
     LKHLQSASFV QSVTEEAVEA FCRDFEFVEG MIIGADEARG RVHIKRMEDG SDAGVQDDVA
     TESGKVSDGD EQESKLRRLF PRTTGEIRVL LS