ID   COG6_ASPNC              Reviewed;         716 AA.
AC   A2QLL1;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=cog6; ORFNames=An06g01630;
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=425011;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA   Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA   van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA   Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA   Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA   Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA   Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA   Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR   EMBL; AM270115; CAK48006.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2QLL1; -.
DR   PaxDb; A2QLL1; -.
DR   EnsemblFungi; CAK48006; CAK48006; An06g01630.
DR   HOGENOM; CLU_011361_1_0_1; -.
DR   Proteomes; UP000006706; Chromosome 8ER.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..716
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339314"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  79580 MW;  A2D8EA44A61D5347 CRC64;
     MASYFPPNGV ISSHGSTRAS SPASSPLSPP VHQRSNALSN RLTSVLSASY ADSDIRDALE
     TLSLRGIHNT AEVRRQLRLD VQKEVVDSNA EIVRDFGLVA EQLKRIGTVI TNLNQTCDEM
     RKHIVSARQE TTPVLEEASA LMKQRKEAET KQELLEAFTQ HFIVPDEDLL ILTHAEEPID
     DHFFEILARV KQVYRDCEAL LGGENERLGL ELMEKSSRSL NSAYQKLYRW IQKEFRSLNL
     EDPRISSSIR RVLRVLAERP SLFHSCLDFF AEARDYVLSD AFHYALTDAV SGTTGDTNVK
     PIEFSAHDPL RYIGDMLAWV HSTTVSEREA LEALFEVSFD GQKALSDLVN RDLIGVSRAL
     RQRVELVIQG HDDPVTCYKV VNLLSFYQTT FSKLLGPQSN LAELLETLEK FTFKHFETLM
     HDEVNNISTD HSALTPPADL SAPQFLQDAL EVLTSLMKTH EASYGADPIP TPGPKTTSSS
     PPPKDTNSEN KFTPVLHSAL EPFLDLAKSS AADLPSHTTQ TIYLTNIHLT VRTTITPYPF
     ASTTHLSPIQ TALSTLRTDL LDIQYRYLLT SSGLQTLLAA LEPFSPQQPT STDQQKPKPN
     ISDILTLPAF QPQALINISQ QLDDFLPSAL MDATDNLKRV ASATFVKSVT EDAVEAFCRD
     FEFVEGMVIA ADNEARGVDV GEKAVEEGGE DEEGVEKGGL RRLFPRTTGE IRVLLS