ID   COG6_ASPOR              Reviewed;         812 AA.
AC   Q2UUV3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=cog6; ORFNames=AO090009000163;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR   EMBL; AP007150; BAE54662.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2UUV3; -.
DR   SMR; Q2UUV3; -.
DR   STRING; 510516.Q2UUV3; -.
DR   EnsemblFungi; BAE54662; BAE54662; AO090009000163.
DR   VEuPathDB; FungiDB:AO090009000163; -.
DR   HOGENOM; CLU_011361_3_0_1; -.
DR   OMA; RFYQQIM; -.
DR   Proteomes; UP000006564; Chromosome 1.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..812
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339315"
FT   REGION          77..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          665..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   812 AA;  90052 MW;  3ADE04CC43EA819F CRC64;
     MDLENNTIHC STFVQHTYIK LNPVGPIGAG RLPETRSVEE AQQYPTGWKF WLTILTMSAL
     VVLGGLDTNI VATAVPSHAS TRTPSPAASP LSPPATQRSS ALTNRLTSVL SASYADSDIR
     DALETLSLRD IHNTPEVRRQ LRLDVQKEVV DCNAEIVRDF GKVAEQLKRI GTVITSLNQT
     CDEMRKHISL ARQDTAPVLE EASTLMNQKK EAETKQQLLD AFTKHFVVPD DDILVLTSLE
     DPINDQFFEV LARVKQVHRD CEALLGGENQ RLGLELMDKS SRNLNSAYQK LYRWIQKEFK
     SLNLEDPRIS SSIRRALRVL AERPSLFHSC LDFFAEARDY TLSDAFHYAL TDAVSGTAGD
     SNVKPIEFSA HDPLRYIGDM LAWVHSTTVS EREALEALFV ADGEELARGI QAGLSSEPWS
     RIDEHEEVAF DGQKALSDLV NRDLIGVSRA LRQRVELVIQ GHDDPVTCYK VVGLLSFYRT
     TFQKLLGPNS NLAELLVTLE KFTFGHFEAL MKDVVSSLST DHLALTPSED LSTPQFLIDA
     LEGLTSLMKT YEASFGADDT ESTSDENRFT PVLRAAFDPF LELATSSAEE LSNATARAIY
     LTNIHLTART SVSEYSFVST THLNPISTKL SSLRIDLLEI QHRYLLDESG LQVLLTALEP
     FSPSSVAKSS TETEKQDSHP LESQPQQQPN LADIATLPAF QPEALIAVSQ QLDDFLPSAL
     MDATDNLKRL RSAAFVKSVT EEAVEAFCRD FEFVEGMIIG ADEARGKVDV TRVDRGSETG
     AESEKGMEEG ENGWGLRRLF PRTTGEIRVL LS