ID   COG6_ASPTN              Reviewed;         752 AA.
AC   Q0CSR3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=cog6; ORFNames=ATEG_03271;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH476597; EAU36545.1; -; Genomic_DNA.
DR   RefSeq; XP_001212449.1; XM_001212449.1.
DR   AlphaFoldDB; Q0CSR3; -.
DR   SMR; Q0CSR3; -.
DR   STRING; 341663.Q0CSR3; -.
DR   EnsemblFungi; EAU36545; EAU36545; ATEG_03271.
DR   GeneID; 4317326; -.
DR   VEuPathDB; FungiDB:ATEG_03271; -.
DR   eggNOG; KOG3758; Eukaryota.
DR   HOGENOM; CLU_011361_1_0_1; -.
DR   OMA; RFYQQIM; -.
DR   OrthoDB; 1370285at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..752
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339316"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..620
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          702..736
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..729
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   752 AA;  82999 MW;  5ADF5B7D55054BA5 CRC64;
     MASYFPPGAA SSHVSTRSSS PASSPLSPPA QQRSNALSNR LTSVLSASYA DSDIRDALET
     LSLRGIHNTA EVRRQLRLDV QKEVVDSNAE IVRDFGKVAE QLKRIGTVIS SLNQTCEEMK
     KHIVLAKQDT TPVLEEAASL MNQKREAETK QQLLDAFTKH FIVSEEDLLI LTSAEEPIDE
     RFFDLLSRVK QVHRDCEVLL GGENQRLGLE LMEKSSRNLN SAYQKLYKWI QKEFRSLNLE
     DPRISSSIRR ALRVLAERPS LFHSCLDFFA EARDYVLSDA FHYALTDAVT GAGGDNVKPI
     EFSAHDPLRY IGDMLAWVHS TTVSEREALE SLFVADGEEL AKGIQAGLNS EPWSRLDEDE
     TVSFDGQKAL SDLVNRDLTG VSRSLRQRVE LVIQGHDDPV TCYKVANLLS FYRGTFSKLL
     GPRSNLADLL ETLEKFTLRH FETLMRNQVN TLSADHAALI PSDDLSAPEF LQDALDVLTA
     LMKTHEASFG ADVSTDDGDN DSVNRFAPVL RAALDPFLEL AKSTADELPN PTARAIYLTN
     IHLTTRSTIA AYPFASATHL TPLSTALSSL RVDLLAIQHR YLLDASGLQV LLAALEPFSP
     SSTNGPSDTA NDGQQQKQPQ PDIADIANLP AFQPDALVAT SQQLDDFLPS ALMDATDNLK
     RVQNASFAKS VTEEAVEAFC RDFEFVEGMI IGADEARAKV DVTRDRAVED DSASDSDKDK
     DEDGDEDEDA EKGLGLRRLF PRTTGEIRVL LS