COG6_CAEEL
ID COG6_CAEEL Reviewed; 642 AA.
AC Q21270;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE Short=COG complex subunit 6;
DE AltName: Full=Component of oligomeric Golgi complex 6;
GN Name=cogc-6; ORFNames=K07C11.9;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Required for normal Golgi function. {ECO:0000250}.
CC -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC composed of eight different subunits and is required for normal Golgi
CC morphology and localization. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR EMBL; FO080570; CCD64764.1; -; Genomic_DNA.
DR PIR; C89124; C89124.
DR RefSeq; NP_505118.1; NM_072717.4.
DR AlphaFoldDB; Q21270; -.
DR SMR; Q21270; -.
DR BioGRID; 44243; 4.
DR IntAct; Q21270; 2.
DR STRING; 6239.K07C11.9; -.
DR EPD; Q21270; -.
DR PaxDb; Q21270; -.
DR PeptideAtlas; Q21270; -.
DR EnsemblMetazoa; K07C11.9.1; K07C11.9.1; WBGene00019481.
DR GeneID; 179201; -.
DR KEGG; cel:CELE_K07C11.9; -.
DR UCSC; K07C11.9; c. elegans.
DR CTD; 179201; -.
DR WormBase; K07C11.9; CE07351; WBGene00019481; cogc-6.
DR eggNOG; KOG3758; Eukaryota.
DR GeneTree; ENSGT00390000013518; -.
DR HOGENOM; CLU_426569_0_0_1; -.
DR InParanoid; Q21270; -.
DR OMA; TVRQVCI; -.
DR OrthoDB; 1370285at2759; -.
DR PhylomeDB; Q21270; -.
DR Reactome; R-CEL-6807878; COPI-mediated anterograde transport.
DR Reactome; R-CEL-6811438; Intra-Golgi traffic.
DR PRO; PR:Q21270; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00019481; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR GO; GO:0035262; P:gonad morphogenesis; IMP:WormBase.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0030334; P:regulation of cell migration; IMP:WormBase.
DR InterPro; IPR010490; COG6.
DR PANTHER; PTHR21506; PTHR21506; 1.
DR Pfam; PF06419; COG6; 1.
DR SMART; SM01087; COG6; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..642
FT /note="Conserved oligomeric Golgi complex subunit 6"
FT /id="PRO_0000213515"
SQ SEQUENCE 642 AA; 73601 MW; 656ED1307B8065A5 CRC64;
MSVIDKTSSA VNPLREKVTT ACAKKLYNDK DCIKIADFIT PLVEDMNLDS NVDRKLHNKL
ERYELRLNKE YLSEFEKINN IVQKFDELCV KMNSTCTNLS KQMETVKFKS VDLVQKTASL
KEKKASIESR CNMINEFLEN YSLSSEELRE LDECEQSGHL SEFFFKVLER CHEIRENCRN
MVQEQGHLAA FEVMEKMQKI DERSHAIICN NLKREFQNLT VDSHQKKQIL SKAFKIISQN
DAVFQLAIDQ YISSRSQELL NQFVEINKMA VQMPEGLAEP LKAVGDMLTS IHELTEQEKQ
LFSSICSAEN LPIVLDECLK SLTSPFKIRV EQLLSTEKNA ITIFKMGNIL IFYANKFETL
IRKDSYFTIM LADLVKTVRQ VCIAGINHHV DGLMRKMTSP HYDLLPVPEV RQCLSLYHGL
ISIAVKTGDL NLLLEPERIY EYVLEPLIQT VQLSATRLKS DIEVSVFTIN CLTVIRSAIS
EISAFKKKIE MIDAMIEGNS DVLVSVQVSE MLEKSGILEL YQKFNAVNPA EKKPLSTLPG
LESTTVGEAI VMFTQYLHNH ASSDHTYDID QQILASEERQ RIRERNTLEF LKVYKMIVDR
LGNPTNGYEN LHYLPIEHVE SVLKFEKEKE NTPSSNESES LA