ID   COG6_CANGA              Reviewed;         832 AA.
AC   Q6FTL7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=COG6; OrderedLocusNames=CAGL0G01496g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR   EMBL; CR380953; CAG59354.1; -; Genomic_DNA.
DR   RefSeq; XP_446427.1; XM_446427.1.
DR   AlphaFoldDB; Q6FTL7; -.
DR   SMR; Q6FTL7; -.
DR   STRING; 5478.XP_446427.1; -.
DR   PRIDE; Q6FTL7; -.
DR   EnsemblFungi; CAG59354; CAG59354; CAGL0G01496g.
DR   GeneID; 2888193; -.
DR   KEGG; cgr:CAGL0G01496g; -.
DR   CGD; CAL0137579; COG6.
DR   VEuPathDB; FungiDB:CAGL0G01496g; -.
DR   eggNOG; KOG3758; Eukaryota.
DR   HOGENOM; CLU_017837_0_0_1; -.
DR   InParanoid; Q6FTL7; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:EnsemblFungi.
DR   GO; GO:0032258; P:cytoplasm to vacuole transport by the Cvt pathway; IEA:EnsemblFungi.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:EnsemblFungi.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..832
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339318"
SQ   SEQUENCE   832 AA;  96282 MW;  807B83487B93E657 CRC64;
     MEFIDYQAFE TAPDNNDKSG TNGEVSLPEP VSRLNISSFS LDYKPLKDNF KLPSILSNVE
     TSLLQTKADV QDDTAMAQKL KKDTSNLYDR MSDYVDLSIQ NFGTKNIKDS TPIPEATTRK
     TLVEPSSIDL EKSNEILAKK LSKVLNEYDT SYHHTIKLRK SLKILEKNRD KLGISEEKLI
     SPDYIGTLAR KSLRTDLETQ LLKDHVTVLE DFKPIVRRIK RLAAPVQQIE NIGEEILKND
     KETFSQKYIS DIDDCRNHLL KLEIKKKILK ALQSKFTLNQ LEDDLIENGP LKEEIFDIVD
     KLTKMKEHAT YLLALPNSKA GEVLIKQTNI TLDTINKKIS NYLIDYMYTF ESNSNMGTKH
     VIDPTERNLA LFQKGLVYLS NDIQYYDDFL KRVTTMRSKT LLDEFLSQFG TTSELSTTIS
     SSEDPVRYIG DVLATIHTMI ANEVDFVKSL FKFTSEDMDK SSSMIINNNA QYFDGLDLKL
     VNDIVQYLAN SCKLRIEQVI RFEENKVINF EITQLLDLYS SMFVNKGIRD DNPLVLHLIQ
     LRDISEKKII NSLTKQLAET ENTQISSPDL LPPQWLSDYL NSITELFDHV ERLYGGKRFS
     KDDIDSDKYM FPYDTLKTVI EEPFMTSLIK QIKDSYPLAK KKEEIRIVML TLQINCFEMI
     NFRLQPYSLS IFSYDESCKH ILENIQHTLD ETVEKLQKLQ ISLLFERTGL NMYYNLMNMI
     FPIDSIQDEI DYDMYMSLVD NPLMSLENLE KNIHEKLNDY LPQALPDFQD NLLIKLTSPS
     IADDVCEICF RTLTDFYCIF RRILKHLYPD NKEKVEAILN FTESEFKTLA GV