COG6_CHAGB
ID COG6_CHAGB Reviewed; 690 AA.
AC Q2HH52;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE Short=COG complex subunit 6;
DE AltName: Full=Component of oligomeric Golgi complex 6;
GN Name=COG6; ORFNames=CHGG_00452;
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC is involved in intra-Golgi protein trafficking. COG is located at the
CC cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC and possibly a number of other membrane trafficking events (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR EMBL; CH408029; EAQ92217.1; -; Genomic_DNA.
DR RefSeq; XP_001219673.1; XM_001219672.1.
DR AlphaFoldDB; Q2HH52; -.
DR SMR; Q2HH52; -.
DR STRING; 38033.XP_001219673.1; -.
DR PRIDE; Q2HH52; -.
DR EnsemblFungi; EAQ92217; EAQ92217; CHGG_00452.
DR GeneID; 4387544; -.
DR eggNOG; KOG3758; Eukaryota.
DR HOGENOM; CLU_011361_1_0_1; -.
DR InParanoid; Q2HH52; -.
DR OMA; RFYQQIM; -.
DR OrthoDB; 1370285at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR010490; COG6.
DR PANTHER; PTHR21506; PTHR21506; 1.
DR Pfam; PF06419; COG6; 1.
DR SMART; SM01087; COG6; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..690
FT /note="Conserved oligomeric Golgi complex subunit 6"
FT /id="PRO_0000339319"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 76737 MW; 716EDE01AB3955BC CRC64;
MSSSSGPLSP QSTTATSSLA AKAANPLSSK VTTVLSSSYA DTEFREALAL LDERGVQNTA
ETRRQLRLDL QKEVIDSNGE IIDEFAKVAE QLRRIGTTIG RLNETFNEMK TQIGSAQKTT
SSTLIEASQL MIQRRQVEQK QALLGAFNTN FVLSEDETAA LTLTSEPVDD LFFAVLAKAK
RISKDCEILL GFENQTLGLE IMEQTSKNLN LGFQKLYKWV QREFKTLNLE NPQIGSSIRH
ALRVLAERPS LFQNCLDFLA EAREHVLSNS FHTALTGSSP SGIEDQSVKP IELVAHDTLR
YVGDMLAWAH SAAVGEREAL EGLFIGEGDE IAKGIQAGRD NEIWRLVAED GEVSDTFDAV
ETLNELVDRD LSGAARLLRQ RVEQVIQTNE ETILAYKLAN LLNFYKSTFS RLLSVGSALV
ETLGALESEA LRQFRSLARD HVAAIQGDFQ HTPADLRPPE FLLGALEQLA AIMKTYETSF
TSSSDREEEF EPVLAEAFDP FISGSANMAK PLRAPSNSIF LINCLLTAER SLSRFDFTQR
RAARLQAQIQ EERARLVETQ YRFFRGESGL DSLIVQLEPL GESKEDIQKA LLLESLQSPA
LSQASQKLDD FLPSALMDAM ENLKNLQDSR LVQSITEEAA EKFCVDFEHV EEMLILVDEA
TEQKQNEQDD IQGPRTLFPR TSGEIRVLLS