ID   COG6_DEBHA              Reviewed;         775 AA.
AC   Q6BPU6;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=COG6; OrderedLocusNames=DEHA2E10736g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR   EMBL; CR382137; CAG88013.2; -; Genomic_DNA.
DR   RefSeq; XP_459774.2; XM_459774.1.
DR   AlphaFoldDB; Q6BPU6; -.
DR   SMR; Q6BPU6; -.
DR   STRING; 4959.XP_459774.2; -.
DR   PRIDE; Q6BPU6; -.
DR   EnsemblFungi; CAG88013; CAG88013; DEHA2E10736g.
DR   GeneID; 2902690; -.
DR   KEGG; dha:DEHA2E10736g; -.
DR   VEuPathDB; FungiDB:DEHA2E10736g; -.
DR   eggNOG; KOG3758; Eukaryota.
DR   HOGENOM; CLU_017837_0_0_1; -.
DR   InParanoid; Q6BPU6; -.
DR   OMA; IINMICP; -.
DR   OrthoDB; 1370285at2759; -.
DR   Proteomes; UP000000599; Chromosome E.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..775
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339322"
SQ   SEQUENCE   775 AA;  88725 MW;  9F78B28B906DE2FF CRC64;
     MDFIDFDSFQ QDEIPQPQPA LSLPITSNIE NLGKRFSNFN SLTKNLLKFD EKDDIKVDGD
     ESEETKLAEK YANLSLNLIN SLEDDNEEEN ESDLNRSKTT TTLSTRLSRV LNNSMPDSLV
     REIFANLDLK IENIAALVEP GITGSNSRKK LRGEIENDLI KTQGLMLKEY QPVIKNLSNL
     ENDLKNLNGL RDSITEKVNK DFQSTKDLNG EVKNLNDTKS LINLKKGLLI SFQNKFALDV
     YEEYVLQNGE INDEFFQVLI KCEKIHENCS ILLSVDNPQL GLKIMSKFNQ LINKSVERII
     NFTNKTLNNL YSLNTTTKLT TLHQCLKFLR KRLNYFNTVI DNFVDTRSRL IIDEFLNQIN
     GDLDKSGDNR SGSIQHDRPI ILSAHDPVRF IGDLLAYIHS VVVNETETIS SIFGISKEEN
     EDDDIEYKDI IDDVTGRILN SLSRSVKSKI EQVITSETKL ATIYAIYSLV ELYTIMFAKH
     LKESSNDKHN LLMTVRELVS SSQNKIISII QNKLTTIKSS NSAQLELNTD LQPPEWIIEF
     YSDILPIIDQ NTSDTFMNLS TENNAEFMKM IINKPIEIFN EHIENNISKL FNRRDQVILK
     LNFLDLILSK IMPIILLSDK ILELNDLTEK LSLELTNLQL DSLISGCQLT NFYNIINMIC
     PFSDDFFDVS IYQPITENKL FSEDNIIAAN DIIQNFLPSA LLDIQQSLFK VNSPMIVNNI
     ITNSSLEFIK FYLKFNLIIN EYLDDASLIW SDIEVATLLG VEEPYQQTKK SMSFD