ID   COG6_DICDI              Reviewed;         673 AA.
AC   Q54CT0;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=cog6; ORFNames=DDB_G0292784;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for normal Golgi function. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC       composed of eight different subunits and is required for normal Golgi
CC       morphology and localization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR   EMBL; AAFI02000196; EAL61066.1; -; Genomic_DNA.
DR   RefSeq; XP_629461.1; XM_629459.1.
DR   AlphaFoldDB; Q54CT0; -.
DR   STRING; 44689.DDB0237952; -.
DR   PaxDb; Q54CT0; -.
DR   EnsemblProtists; EAL61066; EAL61066; DDB_G0292784.
DR   GeneID; 8628851; -.
DR   KEGG; ddi:DDB_G0292784; -.
DR   dictyBase; DDB_G0292784; cog6.
DR   eggNOG; KOG3758; Eukaryota.
DR   HOGENOM; CLU_011361_3_0_1; -.
DR   InParanoid; Q54CT0; -.
DR   OMA; RFYQQIM; -.
DR   PhylomeDB; Q54CT0; -.
DR   Reactome; R-DDI-6807878; COPI-mediated anterograde transport.
DR   Reactome; R-DDI-6811438; Intra-Golgi traffic.
DR   PRO; PR:Q54CT0; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..673
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000328219"
SQ   SEQUENCE   673 AA;  77100 MW;  E56012E387F589DD CRC64;
     MNSTLSRKIQ KVLDIKLDSE DLSNALEELS TFYTSNSIGA RRNLRNEIEK RYLDINIQFL
     DQFDQLNKNI NELVLDFEGI KNSCVDICDH LNSTNRVSSE LLKNAHELSC GLKEIKEKEN
     TLQQFFKKFK LTPQEEQSLV KKEIDSSFYQ TLDRLSEIQN ECKKNLLSNQ YQKPTYEILE
     IITKHQDNAY RRLYQWTKEE IKQLLIIEIP ILDSFNNIDQ QQQQQQQKVM MLPIALSALQ
     NKPLLFKHCL DEISECRTKT ISNGFITALS FGGPNGIPRP IEINAHDPQR YLGDMLAWIH
     QCLASEFELI STILSKVTIK LNENNNNNVD DNIENNNNNN NNNEELNFIE PIIKVLNNSF
     ECINRPLSIR IDQILQSKPG VIITYKMISL LDFYSRMANL ITKGSGVCRV STIFGSIKSN
     CLSVFFTQIK DNFDRLERSP TVPSPQDLLP TNDIKDSINK LSELISTFNS SLIPLDEREK
     EYTPVFSSFI QKIINLTTFS ATSSKLPLIS MAVFMINCLS SIKSVLENYT SFTASNLELL
     TCQIEAHMDT LVEEQTSELL QQMGIGPKLS ILQYSDNKSP LSQIIAMDRL SIVQSIRQFD
     NCLEQSFGTL LMPNCEKLSD TTLRSLSKKS VSNLISVAYS SLYSAIHDPF NQYDEPNSIF
     QYKPDQIKTM LDF