ID   COG6_EMENI              Reviewed;         739 AA.
AC   C8V7C6; Q5B6V7;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=cog6; ORFNames=AN10441;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAA59931.1; Type=Erroneous gene model prediction; Note=The predicted gene AN3723 has been split into 2 genes: AN10466 and AN10441.; Evidence={ECO:0000305};
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DR   EMBL; AACD01000061; EAA59931.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; BN001302; CBF75527.1; -; Genomic_DNA.
DR   RefSeq; XP_661327.1; XM_656235.1.
DR   AlphaFoldDB; C8V7C6; -.
DR   STRING; 162425.CADANIAP00005000; -.
DR   EnsemblFungi; CBF75527; CBF75527; ANIA_10441.
DR   EnsemblFungi; EAA59931; EAA59931; AN3723.2.
DR   GeneID; 2873139; -.
DR   KEGG; ani:AN3723.2; -.
DR   VEuPathDB; FungiDB:AN10441; -.
DR   eggNOG; KOG3758; Eukaryota.
DR   HOGENOM; CLU_278982_0_0_1; -.
DR   InParanoid; C8V7C6; -.
DR   OMA; RFYQQIM; -.
DR   OrthoDB; 1370285at2759; -.
DR   Proteomes; UP000000560; Chromosome II.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 1.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..739
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000399682"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          686..706
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   739 AA;  81668 MW;  BD2D0689C29EA384 CRC64;
     MATGSYFPPP GAPSSISPRN STPALSPLSP PLQQRSNALS NRLTSVLSVS YADSDIRDAL
     ETLSLRGVHN TAEVRRQLRL DVQKEVVDCN AEIVRDFGNV AEQLKRIGSV ISSLKETCDE
     MRKHIVLAKQ DTTPVLEEAS ALMIQKQEAE TKQRLLDAFT KHFIVSEEEL LALTSIEEPI
     DDEFFDVLAR VKQVHRDCEA LLGAEHERLG LELMEKSSRS LNSAYQKLYR WIQKEFKSLN
     LEDPQISGTI RQALRVLAER PSLFQTCLDF FAEARDYVLS DAFHYALTDA VSGGDSAVKP
     IEFSAHDPLR YIGDMLAWVH STTVSEREAL ETLFVAEGDE LAKGIQAGLN SEPWSRIDED
     EEMTFDGQKA LSDLVSRDLI GVARSLRQRV ELVIQGHDDP VTCYKVINLL SFYQTIFSKL
     VGPNSNLAEL LKALEKFTLN HFQTIMRDEV NNISTDHSAL APPDDLSAPQ FLHDSLEVLT
     ALMKTHEASL GTEDPSITSE SEENEFTPVL HAALDPFFTL AKASADELPD PTARAIYLTN
     VHITTRSTIS PYPFATSTHL PPLSATLSTL RVELLESQHR YLLDTSGLQV LLTALQPFSQ
     SNESGTEKDL AAIADLPAFQ AEALISTSQQ LDDFLPSALM DATDNLKRVQ SATFVKSVTE
     EAVEAFCRDF EFVEGMIIGA DEARGVGQSD GAVNEEGEEG DGDGDGEVEL ELEVEQRGQG
     QSLRKLFPRT TGEIRVLLS